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What is Seroquel XR?

Seroquel® XR is the extended release preparation of quetiapine, an atypical antipsychotics. It is used in the treatment of schizophrenia and bipolar disorder. Off label it is used for psychosis in autistic children and for psychosis/agitation related to Alzheimer's dementia.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Bipolar Disorder 69 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar II Disorder 30 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Bipolar I Disorder 30 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Insomnia 26 10 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Mood swings 17 8 Efficacy_major Efficacy_moderate Efficacy_slight
Bipolar rapid cycling 14 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell

See all 138 patients currently taking Seroquel XR

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Reported Side Effects

Side effects as an overall problem

Severe
13
Moderate
33
Mild
12
None
9

Commonly reported side effects, conditions, and hospitalizations associated with Seroquel XR

Weight gain 13
Drowsiness 12
Dizziness 9
Increased appetite 7
Fatigue 5
Insomnia 4
See all 72 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Seroquel XR. See all 18 dosages

  25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily 400 mg daily 600 mg daily 800 mg daily
  7 Number of Patients: 7 22 Number of Patients: 22 3 Number of Patients: 3 18 Number of Patients: 18 15 Number of Patients: 15 13 Number of Patients: 13 27 Number of Patients: 27 16 Number of Patients: 16 8 Number of Patients: 8 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Seroquel XR (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 42   Side effects too severe: 56%
Doctor's advice 21   Doctor's advice: 28%
Did not seem to work 19   Did not seem to work: 25%
Other 8   Other: 11%
Course of treatment ended 5   Course of treatment ended: 7%
Change in health plan coverage 5   Change in health plan coverage: 7%
Expense 4   Expense: 5%
Not indicated 3   Not indicated: 4%
Personal research 2   Personal research: 3%

See all 72 patients who’ve stopped taking Seroquel XR

Currently Taking Seroquel XR

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Seroquel XR

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Seroquel XR

Always
53 79%
Usually
10 15%
Sometimes
1 1%
Never
3 4%

Burden

Difficulty being on treatment

Burden of Seroquel XR

Very
5 7%
Somewhat
14 21%
A little
14 21%
Not at all
34 51%

Cost

Paid out of pocket

Cost of Seroquel XR

$200+
4 9%
$100-199
4 9%
$50-99
5 11%
$25-49
10 23%
< $25
21 48%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.