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What is Donepezil?

Donezpil hydrochloride is an aceytlcholineserase inhibitor used in the treatment of Alzheimer's Disease. It is considered a potentially useful treatment for other neurological conditions including ALS.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Brain fog 39 8 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Memory problems 32 10 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Cognitive impairment 28 16 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Memory lapses (brain blinks) 23 9 Efficacy_major Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 15 1 Efficacy_major
Cognitive Confusion 10 2 Efficacy_major Efficacy_slight

See all 125 patients currently taking Donepezil

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Reported Side Effects

Side effects as an overall problem

Severe
 5
Moderate
 2
Mild
 7
None
 27

Commonly reported side effects, conditions, and hospitalizations associated with Donepezil

Sleep problems 3
Mood swings 2
Diarrhea 2
Nausea 2
More intense dreams 2
Vivid dreams 1
See all 9 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

  daily 2.5 mg daily 5 mg daily 10 mg daily 15 mg daily 20 mg daily 23 mg daily
  4 Number of Patients: 4 1 Number of Patients: 1 38 Number of Patients: 38 79 Number of Patients: 79 3 Number of Patients: 3 5 Number of Patients: 5 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Donepezil (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 25   Did not seem to work: 52%
Side effects too severe 13   Side effects too severe: 27%
Doctor's advice 8   Doctor's advice: 17%
Expense 7   Expense: 15%
Other 4   Other: 8%
Course of treatment ended 3   Course of treatment ended: 6%
Personal research 2   Personal research: 4%

See all 47 patients who’ve stopped taking Donepezil

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Donepezil

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Donepezil

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Donepezil

Always
 36 88%
Usually
 3 7%
Sometimes
 0 0%
Never
 2 5%

Burden

Difficulty being on treatment

Burden of Donepezil

Very
 4 10%
Somewhat
 2 5%
A little
 1 2%
Not at all
 34 83%

Cost

Paid out of pocket

Cost of Donepezil

$200+
 1 4%
$100-199
 0 0%
$50-99
 1 4%
$25-49
 8 30%
< $25
 17 63%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.