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What is Quinine?

Quinine is an antimalarial agent. It is used off label for the prevention and treatment of nocturnal leg cramps. As of February 2007 the only quinine-containing product approved by the US Food and Drug Administration is Qualaquin.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Cramps 42 10 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Stiffness/Spasticity 26 1 Efficacy_moderate
Other 21 3 Efficacy_major
Cramps in legs 11 1 Efficacy_slight
Pain 8 1 Efficacy_cant_tell
ALS (Amyotrophic Lateral Sclerosis) 7 0

See all 83 patients currently taking Quinine

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Reported Side Effects

Side effects as an overall problem

Severe
 2
Moderate
 1
Mild
 0
None
 19

Commonly reported side effects, conditions, and hospitalizations associated with Quinine

Ringing in ears (tinnitus) 2
Blurry vision 2
Nausea 1
Headaches 1
Speech problems 1
left pinkie finger not straight, and 2nd finger the same. 1

Reported Dosages

Frequently reported dosages based on patients currently taking Quinine. See all 29 dosages ►

  daily 325mg as needed 200 mg daily 260 mg daily 300 mg daily 324 mg daily 325 mg daily 350 mg daily 400 mg daily 648 mg daily
  4 Number of Patients: 4 3 Number of Patients: 3 5 Number of Patients: 5 9 Number of Patients: 9 15 Number of Patients: 15 13 Number of Patients: 13 6 Number of Patients: 6 2 Number of Patients: 2 3 Number of Patients: 3 5 Number of Patients: 5  

Reported Stop Reasons

Why Patients Stopped Taking Quinine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 18   Other: 41%
Doctor's advice 8   Doctor's advice: 18%
Did not seem to work 7   Did not seem to work: 16%
Side effects too severe 6   Side effects too severe: 14%
Personal research 4   Personal research: 9%
Course of treatment ended 4   Course of treatment ended: 9%
Expense 2   Expense: 5%
Change in health plan coverage 2   Change in health plan coverage: 5%

See all 44 patients who’ve stopped taking Quinine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Quinine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking Quinine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Quinine

Always
 20 91%
Usually
 1 5%
Sometimes
 1 5%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Quinine

Very
 1 5%
Somewhat
 1 5%
A little
 1 5%
Not at all
 19 86%

Cost

Paid out of pocket

Cost of Quinine

$200+
 0 0%
$100-199
 0 0%
$50-99
 4 33%
$25-49
 2 17%
< $25
 6 50%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.