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What is Desvenlafaxine?

Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Depressed mood 165 69 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Major Depressive Disorder 59 18 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Anxious mood 40 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 32 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 31 15 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar Disorder 17 5 Efficacy_moderate Efficacy_slight Efficacy_none

See all 296 patients currently taking Desvenlafaxine

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Reported Side Effects

Side effects as an overall problem

Severe
29
Moderate
28
Mild
36
None
40

Commonly reported side effects, conditions, and hospitalizations associated with Desvenlafaxine

Nausea 13
Tiredness increased 12
Increased energy 12
Sedation 10
Sluggishness 9
Depressed mood 8
See all 79 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Desvenlafaxine. See all 13 dosages

  1 mg daily 1 other daily 2 mg daily 50 mg m,w,f 50 g daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily
  4 Number of Patients: 4 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 175 Number of Patients: 175 2 Number of Patients: 2 94 Number of Patients: 94 9 Number of Patients: 9 9 Number of Patients: 9  

Reported Stop Reasons

Why Patients Stopped Taking Desvenlafaxine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 47   Did not seem to work: 46%
Side effects too severe 40   Side effects too severe: 39%
Expense 20   Expense: 19%
Other 16   Other: 16%
Doctor's advice 15   Doctor's advice: 15%
Personal research 6   Personal research: 6%
Change in health plan coverage 3   Change in health plan coverage: 3%
Course of treatment ended 1   Course of treatment ended: 1%
Not indicated 1   Not indicated: 1%

See all 101 patients who’ve stopped taking Desvenlafaxine

Currently Taking Desvenlafaxine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Desvenlafaxine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Desvenlafaxine

Always
110 83%
Usually
19 14%
Sometimes
2 2%
Never
2 2%

Burden

Difficulty being on treatment

Burden of Desvenlafaxine

Very
10 8%
Somewhat
11 8%
A little
16 12%
Not at all
96 72%

Cost

Paid out of pocket

Cost of Desvenlafaxine

$200+
3 3%
$100-199
4 5%
$50-99
18 21%
$25-49
27 31%
< $25
34 39%

Report created on February 11, 2012.