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What is Divalproex sodium?

Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migraines.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Epilepsy 333 107 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 115 47 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar Disorder 102 39 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Migraine headaches 44 12 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Bipolar manic episodes 43 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 28 9 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell

See all 618 patients currently taking Divalproex sodium

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Reported Side Effects

Side effects as an overall problem

Severe
 76
Moderate
 76
Mild
 83
None
 50

Commonly reported side effects, conditions, and hospitalizations associated with Divalproex sodium

Weight gain 71
Hair loss (alopecia) 26
Fatigue 26
Drowsiness 22
Nausea 11
Tremor 10
See all 152 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Divalproex sodium. See all 40 dosages ►

  125 mg daily 250 mg daily 500 mg daily 750 mg daily 1,000 mg daily 1,250 mg daily 1,500 mg daily 1,750 mg daily 2,000 mg daily 2,500 mg daily
  17 Number of Patients: 17 52 Number of Patients: 52 124 Number of Patients: 124 59 Number of Patients: 59 171 Number of Patients: 171 11 Number of Patients: 11 89 Number of Patients: 89 11 Number of Patients: 11 63 Number of Patients: 63 13 Number of Patients: 13  

Reported Stop Reasons

Why Patients Stopped Taking Divalproex sodium (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 156   Side effects too severe: 52%
Did not seem to work 109   Did not seem to work: 37%
Doctor's advice 76   Doctor's advice: 26%
Other 54   Other: 18%
Personal research 20   Personal research: 7%
Expense 17   Expense: 6%
Course of treatment ended 8   Course of treatment ended: 3%
Not indicated 5   Not indicated: 2%
Change in health plan coverage 2   Change in health plan coverage: 1%

See all 287 patients who’ve stopped taking Divalproex sodium

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Divalproex sodium

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Divalproex sodium

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Divalproex sodium

Always
 235 82%
Usually
 35 12%
Sometimes
 9 3%
Never
 6 2%

Burden

Difficulty being on treatment

Burden of Divalproex sodium

Very
 25 9%
Somewhat
 52 18%
A little
 60 21%
Not at all
 148 52%

Cost

Paid out of pocket

Cost of Divalproex sodium

$200+
 12 7%
$100-199
 9 5%
$50-99
 21 11%
$25-49
 35 19%
< $25
 102 56%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.