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Home > Community Treatment Reports > Bupropion Treatment Report
What is Bupropion?

Bupropion, a norepinephrine and dopamine reuptake inhibitor (NDRI) antidepressant is used for the treatment of major depressive disorder, including seasonal affective disorder (SAD) and as an adjunct in smoking cessation. Off label used for Attention-deficit/hyperactivity and bipolar disorders.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken
# of patients Efficacy
Major
Moderate
Slight
None
Can’t tell
# of patients evaluated by
Treat my mood condition(s) 342 73
Depression 267 108
Major Depressive Disorder 65 25
Bipolar Disorder 36 13
Other 27 9
Anxiety 20 8

See all 721 patients currently taking Bupropion

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe
30 14%
Moderate
38 17%
Mild
70 32%
None
81 37%

Most commonly reported side effects

Agitation
24 18%
Insomnia
22 17%
Headaches
22 17%
dry mouth
21 16%
Dry mouth
20 15%
Shakiness
19 15%
  • Mild
  • Moderate
  • Severe

Dosages

Top 10 dosages based on patients currently taking Bupropion. See all 35 dosages

  150 mg/24 hours daily 350 mg all the time (24/7) daily 0.5 mg daily 10 mg daily 25 mg daily 30 mg daily 37.5 mg daily 40 mg daily 45 mg daily 50 mg daily 55 mg daily 150 mg/24 hours daily 75 mg daily 100 mg daily 150 mcg daily 150 mg/24 hours daily 150 mg daily 200 mg daily 225 mg daily 250 mg daily 2 x 150 mg/24 hours daily 2 x 150 mg/24 hours one time 300 mg/24 hours daily 300 mg daily 348 mg daily 350 mg daily 400 mg daily 3 x 150 mg/24 hours daily 450 mg daily hydrobromide 522 mg/24 hours daily 2 x 300 mg/24 hours daily 600 mg daily 3 x 300 mg/24 hours daily 1000 mg daily
  1 Number of Patients: 1 1 Number of Patients: 1 15 Number of Patients: 15 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1 17 Number of Patients: 17 46 Number of Patients: 46 1 Number of Patients: 1 70 Number of Patients: 70 113 Number of Patients: 113 45 Number of Patients: 45 3 Number of Patients: 3 1 Number of Patients: 1 16 Number of Patients: 16 1 Number of Patients: 1 127 Number of Patients: 127 164 Number of Patients: 164 1 Number of Patients: 1 2 Number of Patients: 2 32 Number of Patients: 32 15 Number of Patients: 15 45 Number of Patients: 45 3 Number of Patients: 3 1 Number of Patients: 1 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1  

Stop Reasons

Why Patients Stopped Taking Bupropion (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe
81 43% Side effects too severe: 43%
Did not seem to work
61 32% Did not seem to work: 32%
Doctor's advice
51 27% Doctor's advice: 27%
Other
43 23% Other: 23%
Expense
17 9% Expense: 9%
Personal research
10 5% Personal research: 5%
Course of treatment ended
8 4% Course of treatment ended: 4%
Not indicated
4 2% Not indicated: 2%
Change in health plan coverage
1 1% Change in health plan coverage: 1%

See all 188 patients who’ve stopped taking Bupropion

Currently Taking Bupropion

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Bupropion

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Always
177 81%
Usually
33 15%
Sometimes
4 2%
Never
5 2%

Burden

Difficulty being on treatment

Very
21 10%
Somewhat
13 6%
A little
48 22%
Not at all
137 63%

Cost

Paid out of pocket

$200+
4 2%
$100-199
4 2%
$50-99
16 7%
$25-49
19 9%
< $25
107 49%

See more information, including instructions, precautions, side effects, and interactions.

Report created on March 22, 2010.