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What is Isotretinoin?

Isotretinoin is an acne product used in the treatment of severe acne unresponsive to conventional therapy. It is being used off label for treatment of children with metastatic neuroblastoma or leukemia that does not respond to conventional therapy.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Acne 11 3 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Acne breakout 11 7 Efficacy_major Efficacy_moderate
Skin problems 2 2 Efficacy_major
Oily facial skin 1 0
Rosacea 1 0

See all 5 patients currently taking Isotretinoin

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 5
Mild
 3
None
 1

Commonly reported side effects, conditions, and hospitalizations associated with Isotretinoin

Dry skin 3
Dry eyes 2
Depressed mood 2
Excessive daytime sleepiness (somnolence) 1
Dizziness 1
Dry mouth (xerostomia) 1
See all 19 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

  40 mg weekly 40 mg daily 60 mg daily 80 mg daily
  1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Isotretinoin (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 11   Course of treatment ended: 65%
Doctor's advice 4   Doctor's advice: 24%
Side effects too severe 3   Side effects too severe: 18%
Other 3   Other: 18%
Did not seem to work 2   Did not seem to work: 12%
Expense 1   Expense: 6%

See all 17 patients who’ve stopped taking Isotretinoin

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Isotretinoin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking Isotretinoin

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Isotretinoin

Always
 9 90%
Usually
 1 10%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Isotretinoin

Very
 1 10%
Somewhat
 4 40%
A little
 1 10%
Not at all
 4 40%

Cost

Paid out of pocket

Cost of Isotretinoin

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 14%
$25-49
 2 29%
< $25
 4 57%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 27, 2012.