I HAVE HAD MS OVER 24 YEARS. MAJOR COMPLAINT MY RIGHT LEG HINDERS MY WALKING. I USE ELBOW CRUTCHES CAN WALK 150' THAN NEED TO SIT AND REST AT A SLOW PACE. I COULD NOT ESTIMATE HOW MANY FALLS I HAVE TAKEN SO SLOWER HELPS. I TRIED BETA-SERON, NOVANTRONE, AVONEX AND TYSABRI. TYSABRI HAS BEEN THE ONLY EFFECTIVE DRUG I HAVE TRIED SHRINKING ALL SIGNS OF PLAQUE ON MY BRAIN IN 6 MONTHS. I HAVE DONE 8 FUSIONS WITH NO SIDE EFFECTS. I AM A POSTMASTER AND WILL RETIRE NEXT MARCH WITH 35 YEARS OF SERVICE. BIG POSITIVE MY BEST FRIEND, MOTHER OF MY 2 SONS AND WIFE OF 36 YEARS. SHE DOES IT ALL.