in 1998 I was diagnosed with major depression & general anixety disorder .they tried every anti depressants that they were & nothing worked until I tryed 300mg bupropion XL & it worked. I also wasn't getting no sleep & they tried me on all kinds of sleeping aids & nothing worked .so they put me on seroquel & it worked & it also helped with my mood swings.and I'm also on alprazolam for my nerves & panic episodes. In 2007 my psychiatrist decided that I had Bi-Polar 2.So that kinda makes you wonder which one is it ? But sometimes when I try to talk to people it's like my mouth is going faster than my brain & things come out of my mouth that make no sense & it's very embarrassing & even trying to write things down on paper I get the letters right in the word but their all in the wrong place. I try to explain it to people that it's like a camera that flashes differant thoughts & pictures in my mind really fast & then there's the times that I hate myself so bad that I feel like I don't deserve to be alive but I don't have enough guts to even do that right. I also have FMS,degenerative joint & disk diease, scoliosis, And last year I had breast cancer I had a mastectomy with chemotherapy treatments. But on the brighter side I do have some good days a little over half the time since I found the right meds.