Amantadine Treatment Report : PatientsLikeMe

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Home > Community Treatment Reports and Side Effects > Amantadine Treatment Report

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What is Amantadine?

Amantadine is an antiviral medication that blocks actions of viruses. It is used to treat and prevent certain strains of influenza A. It is also used to treat Parkinson's Disease and "Parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose	# of patients	# of patients with evaluations Efficacy
Parkinson's Disease	491	102
Fatigue	463	146
Excessive daytime sleepiness (somnolence)	50	19
Other	37	10
Stiffness/Spasticity	36	6
Tremor	32	16

See all 67 reasons taken ▼

See all 924 patients currently taking Amantadine

Mouse over the table for more information

Reported Side Effects

Side effects as an overall problem

Severe	28
Moderate	51
Mild	53
None	194

Commonly reported side effects, conditions, and hospitalizations associated with Amantadine

See all 102 reported side effects ▼ See top 6 reported side effects ▲
Blotchy skin on my legs	12	12
General ill feeling	11	11
Fatigue	10	10
Edema (fluid retention)	10	10
Constipation	9	9
Blurry vision	8	8
Dry mouth (xerostomia)	7	7
Dizziness	6	6
busy in the head	6	6
Blotchy skin	5	5
Insomnia	5	5
Loss of appetite	4	4
Swelling in ankles	3	3
Numbness in lower extremities	3	3
Nausea	3	3
Jittery feeling	3	3
Swelling in feet	3	3
Rash or skin problems	3	3
Auditory hallucinations	2	2
CHF (Congestive heart failure)	2	2
Hair loss (alopecia)	2	2
Edema in feet	2	2
Mottling of skin on legs	2	2
Depressed mood	2	2
Headaches	2	2
Dry eyes	2	2
Urinary retention	2	2
Visual hallucinations	2	2
Sudden complete dry mouth	2	2
Dizziness and feeling faint	1	1
Hangover effect	1	1
Agitation with restlessness	1	1
Groggy in morning	1	1
Nausea and vomiting	1	1
Swelling in ankle	1	1
Skin rash	1	1
Stomach upset	1	1
Edema of extremities	1	1
Flatulence	1	1
Slowed thinking	1	1
Increased fatigue	1	1
Dizziness (vertigo)	1	1
Increased energy	1	1
Rashes (redness, swelling)	1	1
Swelling in legs, feet and ankles	1	1
Weather or temperature sensitivity	1	1
Edema in lower extremities	1	1
Urinary leakage	1	1
Swelling of calves	1	1
Anticipatory anxiety	1	1
Sour stomach	1	1
Fluid retention weight gain	1	1
Ankle edema	1	1
Depression with suicidal thoughts	1	1
Depression with anxiety	1	1
Increased urinary frequency	1	1
Vertigo	1	1
marble skin	1	1
Ear(s) Tingling	1	1
Rash on legs	1	1
Cloudy thinking, particularly with math skills	1	1
Chronic constipation	1	1
Visual pattern	1	1
Dry tongue	1	1
Swelling in legs	1	1
Excessive dry mouth	1	1
Livedo reticularis	1	1
Skin discoloration	1	1
Irregular heartbeat (cardiac arrhythmia)	1	1
Edema in hands	1	1
Discoloration of legs	1	1
Generalized Anxiety Disorder	1	1
Mild Depression	1	1
Hospitalization	1	1
Heartburn	1	1
Low blood pressure	1	1
Bladder problems	1	1
Excessive daytime sleepiness (somnolence)	1	1
Memory problems	1	1
Walking problems	1	1
Balance problems	1	1
Brain fog	1	1
Numbness and Tingling with Pins and Needles	1	1
Weight gain	1	1
Cognitive Confusion	1	1
Chills/fever	1	1
Difficulty sleeping through night	1	1
Decreased appetite	1	1
Slow speech (bradyarthria)	1	1
Dyskinesia	1	1
Hives (urticaria)	1	1
Sleeplessness	1	1
Sex drive (libido) decreased	1	1
Peripheral edema	1	1
Lightheadedness	1	1
Motion sickness	1	1
Tiredness	1	1
Anger	1	1
Loss of energy	1	1
Raynaud's phenomenon	1	1
Drowsiness	1	1
Body Aches	1	1

Reported Dosages

Frequently reported dosages based on patients currently taking Amantadine. See all 36 dosages ►

daily	100mg as needed	2 mg daily	20 mg daily	50 mg daily	100 mg daily	150 mg daily	200 mg daily	300 mg daily	400 mg daily
22	9	3	3	3	267	4	389	163	33

Reported Stop Reasons

Why Patients Stopped Taking Amantadine (multiple reasons could be selected)
Reason	# Patients	Percentage of patients
Did not seem to work	208
Side effects too severe	103
Doctor's advice	80
Other	47
Not indicated	12
Course of treatment ended	11
Expense	10
Personal research	10
Change in health plan coverage	2

See all 377 patients who’ve stopped taking Amantadine

Reported Duration See details about how long patients take this treatment ▼ Reported Duration Hide details ▲

Currently Taking Amantadine

A bar graph

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
3	6	15	39	58	290

Stopped Taking Amantadine

A bar graph

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
51	75	52	65	43	88

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Amantadine

Always	252	77%
Usually	48	15%
Sometimes	9	3%
Never	17	5%

Burden

Difficulty being on treatment

Burden of Amantadine

Very	9	3%
Somewhat	18	6%
A little	42	13%
Not at all	257	79%

Cost

Paid out of pocket

Cost of Amantadine

$200+	3	1%
$100-199	2	1%
$50-99	6	3%
$25-49	19	9%
< $25	179	86%

See more information, including instructions, precautions, side effects, and interactions.

Patient Evaluations

See all 326 patient evaluations

wkikta

Sex: M

Sensation: None

Overall: Mild

Cognition: moderate

Vision: mild

Speech: mild

Swallowing: moderate

Upper limb: mild

Walking: moderate
wkikta

200 mg daily

since Mar 04, 2010
Efficacy Moderate for Fatigue
Side Effects None
Advice/Tips It worked very well for me for quite a while, just not enough anymore. Started Provigil, it is very good. See full evaluation

IlliniMS

Sex: F

Sensation: None

Overall: None

Cognition: none

Vision: none

Speech: none

Swallowing: none

Upper limb: none

Walking: none
IlliniMS

200 mg daily

since May 17, 2010
Efficacy Moderate for Fatigue
Side Effects Severe
Advice/Tips Discontinued due to side effect of Livedo Reticularis See full evaluation