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What is Sulfamethoxazole-Trimethoprim (cotrimoxazole)?

Sulfamethoxazole-trimethoprim, also known as SMX-TMP or cotrimoxazole, is a combination of sulfamethoxazole, an antibacterial sulfonamide, and trimethoprim. The combination eliminates bacteria that cause many kinds of infections, including pneumonia and urinary tract and intestinal infections.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Prevent infection 101 42 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Other 28 10 Efficacy_major Efficacy_moderate Efficacy_none Efficacy_cant_tell
HIV (Human Immunodeficiency Virus) 16 2 Efficacy_cant_tell
Support immune health 15 6 Efficacy_major Efficacy_none Efficacy_cant_tell
General health 15 2 Efficacy_major Efficacy_cant_tell
Bladder problems 12 1 Efficacy_major

See all 256 patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

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Reported Side Effects

Side effects as an overall problem

Severe
 5
Moderate
 5
Mild
 22
None
 62

Commonly reported side effects, conditions, and hospitalizations associated with Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Nausea 2
Weight loss 1
Yeast Infection (candida) 1
Diarrhea 1
Dry eyes 1
Rash or skin problems 1
See all 23 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Sulfamethoxazole-Trimethoprim (cotrimoxazole). See all 50 dosages ►

  400 mg-80 mg weekly 400 mg-80 mg m,w,f 3 x 400 mg-80 mg weekly 800 mg-160 mg m,w,f 3 x 800 mg-160 mg weekly 400 mg-80 mg daily 2 x 400 mg-80 mg daily 800 mg daily 800 mg-160 mg daily 2 x 800 mg-160 mg daily
  7 Number of Patients: 7 11 Number of Patients: 11 14 Number of Patients: 14 9 Number of Patients: 9 7 Number of Patients: 7 94 Number of Patients: 94 8 Number of Patients: 8 7 Number of Patients: 7 34 Number of Patients: 34 5 Number of Patients: 5  

Reported Stop Reasons

Why Patients Stopped Taking Sulfamethoxazole-Trimethoprim (cotrimoxazole) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 74   Course of treatment ended: 56%
Doctor's advice 36   Doctor's advice: 27%
Side effects too severe 19   Side effects too severe: 14%
Other 12   Other: 9%
Did not seem to work 3   Did not seem to work: 2%
Personal research 1   Personal research: 1%
Not indicated 1   Not indicated: 1%

See all 128 patients who’ve stopped taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Sulfamethoxazole-Trimethoprim (cotrimoxazole)

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Always
 82 87%
Usually
 8 9%
Sometimes
 1 1%
Never
 3 3%

Burden

Difficulty being on treatment

Burden of Sulfamethoxazole-Trimethoprim (cotrimoxazole)

Very
 3 3%
Somewhat
 3 3%
A little
 10 11%
Not at all
 78 83%

Cost

Paid out of pocket

Cost of Sulfamethoxazole-Trimethoprim (cotrimoxazole)

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 2%
$25-49
 5 9%
< $25
 50 89%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.