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What is Zidovudine (AZT/ZDV/Azidothymidine)?

Zidovudine, also known as AZT, ZDV and azidothymidine, is an antiretroviral agent used for treatment of HIV infection in combination with at least two other antiretroviral agents. As a monotherapy it is used for the prevention of maternal/fetal HIV transmission.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
HIV (Human Immunodeficiency Virus) 24 7 Efficacy_major Efficacy_none Efficacy_cant_tell
Don't know 1 0
Participate in clinical trial 1 1 Efficacy_none
Chronic Fatigue Syndrome 1 1 Efficacy_major
XMRV infection 1 0

See all 20 patients currently taking Zidovudine (AZT/ZDV/Azidothymidine)

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Reported Side Effects

Side effects as an overall problem

Severe
4
Moderate
3
Mild
0
None
2

Commonly reported side effects, conditions, and hospitalizations associated with Zidovudine (AZT/ZDV/Azidothymidine)

Nausea 2
Dizziness 2
Anemia 2
Lipodystrophy (lipoatrophy or loss of fatty tissue) 1
Vomiting 1
Iron Deficiency Anemia 1

Reported Dosages

  daily 300 mg daily 600 mg daily
  4 Number of Patients: 4 5 Number of Patients: 5 10 Number of Patients: 10  

Reported Stop Reasons

Why Patients Stopped Taking Zidovudine (AZT/ZDV/Azidothymidine) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Doctor's advice 8   Doctor's advice: 50%
Side effects too severe 7   Side effects too severe: 44%
Did not seem to work 2   Did not seem to work: 13%
Personal research 1   Personal research: 6%
Other 1   Other: 6%
Course of treatment ended 1   Course of treatment ended: 6%

See all 15 patients who’ve stopped taking Zidovudine (AZT/ZDV/Azidothymidine)

Currently Taking Zidovudine (AZT/ZDV/Azidothymidine)

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
0

Stopped Taking Zidovudine (AZT/ZDV/Azidothymidine)

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Zidovudine (AZT/ZDV/Azidothymidine)

Always
5 56%
Usually
2 22%
Sometimes
1 11%
Never
1 11%

Burden

Difficulty being on treatment

Burden of Zidovudine (AZT/ZDV/Azidothymidine)

Very
3 33%
Somewhat
2 22%
A little
0 0%
Not at all
4 44%

Cost

Paid out of pocket

Cost of Zidovudine (AZT/ZDV/Azidothymidine)

$200+
1 14%
$100-199
0 0%
$50-99
0 0%
$25-49
0 0%
< $25
5 71%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 12, 2012.