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What is Infliximab?

Infliximab is a monoclonal antibody used in the treatment of rheumatoid arthritis; Crohn's disease; psoriatic arthritis; chronic severe psoriasis; and ankylosing spondylitis. Off label used for acute graft-versus-host disease (GVHD) and juvenile rheumatoid arthritis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
RA (Rheumatoid Arthritis) 37 10 Efficacy_major Efficacy_moderate Efficacy_none
Crohn's Disease 28 8 Efficacy_major Efficacy_moderate Efficacy_slight
Psoriatic Arthritis 20 4 Efficacy_major Efficacy_moderate Efficacy_slight
Ulcerative colitis 10 4 Efficacy_major Efficacy_moderate Efficacy_cant_tell
Ankylosing Spondylitis 9 2 Efficacy_moderate Efficacy_cant_tell
Psoriasis 6 0

See all 85 patients currently taking Infliximab

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Reported Side Effects

Side effects as an overall problem

Severe
 2
Moderate
 7
Mild
 11
None
 10

Commonly reported side effects, conditions, and hospitalizations associated with Infliximab

Joint pain 3
Fatigue 3
Headaches 2
Dizziness 1
Pain in lower back 1
Tiredness 1
See all 20 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Infliximab. See all 50 dosages ►

  100 mg every 3 months 100 mg every 8 weeks 100 mg every 6 weeks 100 mg monthly 100 mg every other week 400 mg every 8 weeks 300 mg monthly 400 mg monthly 500 mg monthly 900 mg every 6 weeks
  7 Number of Patients: 7 6 Number of Patients: 6 5 Number of Patients: 5 4 Number of Patients: 4 6 Number of Patients: 6 4 Number of Patients: 4 4 Number of Patients: 4 5 Number of Patients: 5 3 Number of Patients: 3 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Infliximab (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 14   Did not seem to work: 32%
Side effects too severe 12   Side effects too severe: 27%
Other 10   Other: 23%
Expense 9   Expense: 20%
Doctor's advice 7   Doctor's advice: 16%
Change in health plan coverage 4   Change in health plan coverage: 9%
Not indicated 4   Not indicated: 9%
Personal research 1   Personal research: 2%

See all 41 patients who’ve stopped taking Infliximab

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Infliximab

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Infliximab

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Infliximab

Always
 28 93%
Usually
 0 0%
Sometimes
 2 7%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Infliximab

Very
 1 3%
Somewhat
 12 40%
A little
 11 37%
Not at all
 6 20%

Cost

Paid out of pocket

Cost of Infliximab

$200+
 6 35%
$100-199
 1 6%
$50-99
 3 18%
$25-49
 1 6%
< $25
 5 29%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.