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What is buprenorphine-naloxone?

This is a combination of two medications, buprenorphine and naloxone used to treat opiate drug addiction and withdrawal. Buprenorphine binds to parts of the brain to lower the need for pain drugs and help with withdrawal signs, while naloxone helps prevent abuse of this drug.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Pain 13 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Other 7 2 Efficacy_major
Opiate Addiction 6 2 Efficacy_major
Fibromyalgia 5 2 Efficacy_major Efficacy_slight
Addictive opiate 3 1 Efficacy_major
Back pain 3 1 Efficacy_moderate

See all 39 patients currently taking buprenorphine-naloxone

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 2
Mild
 4
None
 6

Commonly reported side effects, conditions, and hospitalizations associated with buprenorphine-naloxone

Constipation 3
Sex drive (libido) decreased 2
Anxious mood 1
Urinary retention 1
Emotional withdrawal 1
Nausea sometimes 1

Reported Dosages

Frequently reported dosages based on patients currently taking buprenorphine-naloxone. See all 21 dosages ►

  2 mg-0.5 mg daily 2 x 2 mg-0.5 mg daily 8 mg daily 8 mg-2 mg daily 1.5 x 8 mg-2 mg daily 6 x 2 mg-0.5 mg daily 7 x 2 mg-0.5 mg daily 2 x 8 mg-2 mg daily 3 x 8 mg-2 mg daily 4 x 8 mg-2 mg daily
  2 Number of Patients: 2 2 Number of Patients: 2 1 Number of Patients: 1 10 Number of Patients: 10 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 3 Number of Patients: 3 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking buprenorphine-naloxone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Course of treatment ended 2   Course of treatment ended: 50%
Expense 1   Expense: 25%
Personal research 1   Personal research: 25%
Doctor's advice 1   Doctor's advice: 25%
Side effects too severe 1   Side effects too severe: 25%
Other 1   Other: 25%

See all 4 patients who’ve stopped taking buprenorphine-naloxone

Reported Duration See details about how long patients take this treatment ▼

Currently Taking buprenorphine-naloxone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking buprenorphine-naloxone

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of buprenorphine-naloxone

Always
 10 77%
Usually
 3 23%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of buprenorphine-naloxone

Very
 1 8%
Somewhat
 1 8%
A little
 3 23%
Not at all
 8 62%

Cost

Paid out of pocket

Cost of buprenorphine-naloxone

$200+
 2 18%
$100-199
 0 0%
$50-99
 3 27%
$25-49
 3 27%
< $25
 3 27%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.