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What is Glycopyrrolate?

Glycopyrrolate is an anticholinergic drug which slows the activity of the salivary glands, stomach and intestinal tract, thus relieving cramping and reducing acid secretion. It is commonlu used in the treatment of peptic ulcers, but also has a specific use in ALS/MND of reducing excess saliva.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Excess saliva 69 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
ALS (Amyotrophic Lateral Sclerosis) 7 1 Efficacy_moderate
Other 5 0
Excess mucus 3 2 Efficacy_moderate Efficacy_none
Diarrhea chronic 2 0
Drooling 2 0

See all 68 patients currently taking Glycopyrrolate

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Reported Side Effects

Side effects as an overall problem

Severe
 2
Moderate
 2
Mild
 1
None
 16

Commonly reported side effects, conditions, and hospitalizations associated with Glycopyrrolate

Dry mouth (xerostomia) 3
Constipation 1
Dry eyes 1
Dry throat 1

Reported Dosages

Frequently reported dosages based on patients currently taking Glycopyrrolate. See all 19 dosages ►

  1mg as needed daily 0.2 mg/mL daily 0.2 mg daily 1 mg daily 2 mg daily 3 mg daily 4 mg daily 6 mg daily 8 mg daily
  7 Number of Patients: 7 6 Number of Patients: 6 2 Number of Patients: 2 2 Number of Patients: 2 16 Number of Patients: 16 16 Number of Patients: 16 12 Number of Patients: 12 11 Number of Patients: 11 4 Number of Patients: 4 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Glycopyrrolate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 13   Did not seem to work: 59%
Side effects too severe 6   Side effects too severe: 27%
Doctor's advice 2   Doctor's advice: 9%
Other 2   Other: 9%
Expense 1   Expense: 5%
Change in health plan coverage 1   Change in health plan coverage: 5%

See all 22 patients who’ve stopped taking Glycopyrrolate

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Glycopyrrolate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Glycopyrrolate

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Glycopyrrolate

Always
 17 81%
Usually
 2 10%
Sometimes
 1 5%
Never
 1 5%

Burden

Difficulty being on treatment

Burden of Glycopyrrolate

Very
 2 10%
Somewhat
 1 5%
A little
 3 14%
Not at all
 15 71%

Cost

Paid out of pocket

Cost of Glycopyrrolate

$200+
 0 0%
$100-199
 0 0%
$50-99
 2 18%
$25-49
 1 9%
< $25
 8 73%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.