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What is Vitamin B12 (methylcobalamin)?

Methylcobalamin is an old form of B12 that easily crosses the Blood Brain Barrier. In low doses it is believed to strengthen the myelin sheath of nerve axons by sharing its methyl groups. Recently, it has been found to have anti-apoptotic properties but only at very high doses. Read more...Click to read more below

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
General health 41 5 Efficacy_moderate Efficacy_cant_tell
ALS (Amyotrophic Lateral Sclerosis) 37 9 Efficacy_moderate Efficacy_none Efficacy_cant_tell
Fatigue 29 4 Efficacy_moderate Efficacy_slight Efficacy_none
Vitamin B12 deficiency 19 4 Efficacy_major Efficacy_slight Efficacy_none
MS (Multiple Sclerosis) 13 1 Efficacy_major
Other 12 2 Efficacy_major Efficacy_moderate

See all 167 patients currently taking Vitamin B12 (methylcobalamin)

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Reported Side Effects

Side effects as an overall problem

Severe
0
Moderate
1
Mild
3
None
28

Commonly reported side effects, conditions, and hospitalizations associated with Vitamin B12 (methylcobalamin)

Restlessness 1
verry hight in my blood test 1
Dizziness with disorientation 1
Injection site soreness 1

Reported Dosages

Frequently reported dosages based on patients currently taking Vitamin B12 (methylcobalamin). See all 68 dosages

  1 mg daily 5 mg daily 100 mg daily 500 mcg daily 500 mg daily 1,000 mg daily 1,000 mcg daily 2,000 mcg daily 2,000 mg daily 5,000 mcg daily
  8 Number of Patients: 8 9 Number of Patients: 9 5 Number of Patients: 5 5 Number of Patients: 5 6 Number of Patients: 6 16 Number of Patients: 16 20 Number of Patients: 20 6 Number of Patients: 6 6 Number of Patients: 6 6 Number of Patients: 6  

Reported Stop Reasons

Why Patients Stopped Taking Vitamin B12 (methylcobalamin) (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 14   Other: 41%
Did not seem to work 9   Did not seem to work: 26%
Doctor's advice 5   Doctor's advice: 15%
Not indicated 4   Not indicated: 12%
Expense 4   Expense: 12%
Personal research 4   Personal research: 12%
Side effects too severe 2   Side effects too severe: 6%
Change in health plan coverage 1   Change in health plan coverage: 3%

See all 34 patients who’ve stopped taking Vitamin B12 (methylcobalamin)

Currently Taking Vitamin B12 (methylcobalamin)

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Vitamin B12 (methylcobalamin)

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Vitamin B12 (methylcobalamin)

Always
21 66%
Usually
4 13%
Sometimes
4 13%
Never
3 9%

Burden

Difficulty being on treatment

Burden of Vitamin B12 (methylcobalamin)

Very
0 0%
Somewhat
4 13%
A little
6 19%
Not at all
22 69%

Cost

Paid out of pocket

Cost of Vitamin B12 (methylcobalamin)

$200+
1 7%
$100-199
0 0%
$50-99
1 7%
$25-49
1 7%
< $25
12 80%

Report created on February 12, 2012.