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What is Milnacipran?

Milnacipran is a serotonin/norepinephrine reuptake inhibitor (SNRI) antidepressant. It is used in the treatment of depression and has demonstrated significant improvements in multiple aspects of fibromyalgia, including pain, patient global assessment and physical function.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Fibromyalgia 749 305 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Pain 75 27 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 46 13 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Joints ache (whole body) 24 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fatigue 13 5 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
ALL LISTED ABOVE 6 0

See all 769 patients currently taking Milnacipran

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Reported Side Effects

Side effects as an overall problem

Severe
 114
Moderate
 84
Mild
 85
None
 58

Commonly reported side effects, conditions, and hospitalizations associated with Milnacipran

Nausea 56
Sweating excessive 29
Hot flashes 28
Headaches 24
Constipation 22
Dizziness 18
See all 172 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Milnacipran. See all 26 dosages ►

  daily 2 mg daily 12.5 mg daily 20 mg daily 25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily
  72 Number of Patients: 72 5 Number of Patients: 5 43 Number of Patients: 43 3 Number of Patients: 3 75 Number of Patients: 75 128 Number of Patients: 128 9 Number of Patients: 9 390 Number of Patients: 390 34 Number of Patients: 34 110 Number of Patients: 110  

Reported Stop Reasons

Why Patients Stopped Taking Milnacipran (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 182   Side effects too severe: 61%
Did not seem to work 108   Did not seem to work: 36%
Doctor's advice 54   Doctor's advice: 18%
Expense 29   Expense: 10%
Other 18   Other: 6%
Personal research 8   Personal research: 3%
Change in health plan coverage 6   Change in health plan coverage: 2%
Not indicated 5   Not indicated: 2%
Course of treatment ended 3   Course of treatment ended: 1%

See all 286 patients who’ve stopped taking Milnacipran

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Milnacipran

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Milnacipran

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Milnacipran

Always
 298 87%
Usually
 29 9%
Sometimes
 4 1%
Never
 10 3%

Burden

Difficulty being on treatment

Burden of Milnacipran

Very
 28 8%
Somewhat
 34 10%
A little
 67 20%
Not at all
 212 62%

Cost

Paid out of pocket

Cost of Milnacipran

$200+
 4 2%
$100-199
 23 9%
$50-99
 51 21%
$25-49
 83 34%
< $25
 80 33%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.