PatientsLikeMe : Duloxetine Treatment Report

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Duloxetine Treatment Report

Most Popular Brands: Cymbalta

See patients taking Duloxetine

What is Duloxetine?

Duloxetine is used to treat depression and generalized anxiety disorder. It is a selective serotonin/norepinephrine reuptake inhibitors (SSNRIs) used to treat both emotional and physical symptoms of depression, it is prescribed for diabetic peripheral neuropathic pain and management of fibromyalgia.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken	# of patients	# of patients evaluated by
Fibromyalgia	366	116
Depression	169	51
Nerve pain (neuropathic pain)	54	11
Pain, all over (generalized)	52	18
Pain	22	7
Anxiety	18	4
Other	16	7
chronic pain	10	3
Support another treatment	9	4
Bipolar Disorder	4	2
Don't know	2	1
anxiety and moodiness	1	0
migraines	1	0
depression, nerve pain	1	1
depression & nerve pain	1	0
Pain and Depression	1	0
Fibromyalgia and depression	1	1
associated pain from fibromyalgia	1	1
FMS, Depression and Pain	1	0
Fibromyalgia, depression, pain all over.	1	0
pain,depression,fatigue	1	0
Major Depressive Disorder	1	1
Combo of Fibro w/ depression	1	0
Seizures (partial/focal)	1	0
Fibromyalgia and Depression	1	0
Fatigue	1	1
depression and fibro	1	0
Fibro, Depression, Nerve Pain	1	0
Diabetic Neuropathy	1	0
also for sleeping but i also sleep with cpap breathing machine	1	0
Fatigue and sleepiness	1	1
Seasonal affective disorder (SAD)	1	1
neuopathy pain	1	0
Irritable Bowel Syndrome (IBS)	1	1
inability to function on a daily basis	1	0
depression/pain	1	0
occipital neuralgia	1	1
Sleep problems	1	0
Depression & Fibromyalgia	1	0
regulate sleep pattern	1	0
anxiety, depression, confusion, falling down	1	0
Memory problems	1	0
Muscle cramps	1	0
Muscle Pain	1	0
depression w/lower back pain	1	0
Insomnia	1	1

See all 46 reasons taken ▼

See all 619 patients currently taking Duloxetine

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe	27	15%
Moderate	47	27%
Mild	48	27%
None	53	30%

Most commonly reported side effects

increased sweating	51	29%
Brain cloud	45	26%
Sex drive (libido) decreased	44	25%
Dizziness	41	23%
Nausea	39	22%
I feel flat	34	19%
Insomnia	32	18%
Sedation	19	11%
anorgasmia	7	4%
mania	7	4%
Constipation	6	3%
dry mouth	5	3%
Weight gain	4	2%
Hot flashes	3	2%
Loss of appetite	3	2%
Vivid dreams	2	1%
Fatigue	2	1%
Daytime sleepiness	1	1%
sweating/hot flashes	1	1%
Diarrhea	1	1%
saw bugs	1	1%
Mood swings	1	1%
Decreased appetite	1	1%
dry mouth/throat	1	1%
headache	1	1%
Emotions out of control	1	1%
dizziness, fatigue	1	1%
makes me goofy	1	1%
Weird dreams	1	1%
serotonin syndrome	1	1%
Bleed when I take celebrex	1	1%
Seizures STARING episodes	1	1%
Night sweats	1	1%
anxious	1	1%
fall sleep during the day	1	1%
grinding teeth	1	1%
Hoarseness	1	1%
Extreme weight gain	1	1%
shaking hands	1	1%
Increased appetite	1	1%
exhaustion	1	1%
brain zaps	1	1%
Anxiety	1	1%
Agitation/Irritability	1	1%
Weight loss	1	1%
crying for good reason	1	1%
Irritable Bowel Syndrome (IBS)	1	1%
Uro-Genital Syndrome	1	1%
yawning excessively	1	1%
Flu-like symptoms	1	1%
felt high	1	1%
menstruation differences	1	1%
eye twitching	1	1%
Migraine	1	1%
makes me throw up	1	1%
Bruising	1	1%
High blood pressure (Hypertension)	1	1%
Heart Palpitations	1	1%
Nervousness	1	1%
Migraines	1	1%
Aggression	1	1%
Excessive tiredness	1	1%
dry mouth, dry tongue, dry throat	1	1%
Anorexia	1	1%
sore throat	1	1%
makes me sleepy	1	1%
Memory lapses (brain blinks)	1	1%

Mild
Moderate
Severe

See all 67 reported side effects ▼

Dosages

Top 10 dosages based on patients currently taking Duloxetine. See all 19 dosages ►

daily	1 mg daily	2 mg daily	60 mg weekly	15 mg daily	20 mg daily	25 mg daily	30 mg daily	40 mg daily	60 mg daily	80 mg daily	90 mg daily	120 mg daily	130 mg daily	180 mg daily	240 mg daily	270 mg daily	1800 mg daily	5400 mg daily
1	1	1	1	1	37	1	117	7	357	2	51	72	1	2	2	1	1	1

Stop Reasons

Why Patients Stopped Taking Duloxetine (multiple reasons could be selected)
Reason	# Patients	Percentage of patients
Side effects too severe	62	47%
Did not seem to work	38	29%
Doctor's advice	31	23%
Other	17	13%
Expense	16	12%
Personal research	5	4%
Not indicated	1	1%

See all 119 patients who’ve stopped taking Duloxetine

Duration See details about how long patients take this treatment ▼

Currently Taking Duloxetine

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
6	50	70	128	95	127

Stopped Taking Duloxetine

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
30	34	18	11	12	14

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always	150	86%
Usually	19	11%
Sometimes	2	1%
Never	4	2%

Burden

Difficulty being on treatment

Very	18	10%
Somewhat	21	12%
A little	31	18%
Not at all	105	60%

Cost

Paid out of pocket

$200+	4	2%
$100-199	10	6%
$50-99	20	11%
$25-49	38	22%
< $25	46	26%

See more information, including instructions, precautions, side effects, and interactions.

Patient Evaluations

See all 175 patient evaluations

WysOne

Sex: F

Pain: Most

Fatigue: Most

Sleep: Most

Stiffness: All

function: Little

external_stress: None

Stickman: most

Description:F63y

FM:12y Dx

CFS:?y

See profile
WysOne

120 mg daily

since Dec 08, 2008
Efficacy Moderate for Depression
Side Effects None
Advice/Tips This has helped quite a bit for fibromyalgia-related depression. See full evaluation

Brensui

Sex: F

Pain: All

Fatigue: All

Sleep: All

Stiffness: All

function: None

external_stress: Most

Stickman: all

Description:F41y

FM:2y Dx

See profile
Brensui

60 mg daily

since Dec 09, 2008
Efficacy Moderate for Fibromyalgia
Side Effects Moderate
Advice/Tips Start with 30 mg dosage as long as it works for you and is no longer making you sick. Only bump the dosage up if the 30 mg is no longer working for you, no m... See full evaluation

mstaz88

Sex: F

Pain: All

Fatigue: All

Sleep: All

Stiffness: All

function: None

external_stress: All

Stickman: all

Description:F39y

FM:13y Dx

See profile
mstaz88

120 mg daily

since Feb 02, 2009
Efficacy None for Fibromyalgia
Side Effects None
See full evaluation