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What is Propoxyphene?

Propoxyphene is an opioid analgesic used for the management of mild to moderate pain. In 2010 the FDA sought market withdrawal of propoxyphene and requested manufacturers voluntarily remove their products after new clinical data showed potential for serious heart risks.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Pain 18 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 3 2 Efficacy_cant_tell
Increase effect of another treatment 2 1 Efficacy_slight
Migraine headaches 1 0
Myofascial pain syndrome (MPS) 1 0
Stomach pain 1 0

See all 20 patients currently taking Propoxyphene

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 3
Mild
 2
None
 9

Commonly reported side effects, conditions, and hospitalizations associated with Propoxyphene

Elevated blood pressure 1
Heart rate increased 1
Drowsiness 1
Jittery feeling 1
Allergic reaction 1
Generalized itching 1

Reported Dosages

Frequently reported dosages based on patients currently taking Propoxyphene. See all 14 dosages ►

  hydrochloride65mg as needed 40 mg daily 65 mg daily 80 mg daily 100 mg daily 130 mg daily 195 mg daily 260 mg daily 300 mg daily 400 mg daily
  4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3 2 Number of Patients: 2 2 Number of Patients: 2 2 Number of Patients: 2 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Propoxyphene (multiple reasons could be selected)
Reason # Patients Percentage of patients
Other 5   Other: 42%
Did not seem to work 4   Did not seem to work: 33%
Doctor's advice 2   Doctor's advice: 17%
Side effects too severe 1   Side effects too severe: 8%
Course of treatment ended 1   Course of treatment ended: 8%

See all 12 patients who’ve stopped taking Propoxyphene

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Propoxyphene

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
0

Stopped Taking Propoxyphene

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Propoxyphene

Always
 8 57%
Usually
 4 29%
Sometimes
 2 14%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Propoxyphene

Very
 0 0%
Somewhat
 2 14%
A little
 1 7%
Not at all
 11 79%

Cost

Paid out of pocket

Cost of Propoxyphene

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 0 0%
< $25
 5 100%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.