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What is Memantine?

Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system. It is also being tested for use as a cognitive enhancer in a variety of other conditions.

Merz's Memantine site

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
ALS (Amyotrophic Lateral Sclerosis) 18 2 Efficacy_major Efficacy_slight
Cognitive impairment 17 5 Efficacy_major Efficacy_moderate Efficacy_slight
Other 13 2 Efficacy_major Efficacy_moderate
Memory problems 12 3 Efficacy_major Efficacy_moderate Efficacy_slight
Brain fog 11 5 Efficacy_major Efficacy_moderate Efficacy_none Efficacy_cant_tell
Migraine headaches 5 0

See all 88 patients currently taking Memantine

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Reported Side Effects

Side effects as an overall problem

Severe
1
Moderate
3
Mild
4
None
17

Commonly reported side effects, conditions, and hospitalizations associated with Memantine

Constipation 1
Shortness of breath (dyspnea) 1
Vivid dreams 1
Metallic taste in mouth 1

Reported Dosages

Frequently reported dosages based on patients currently taking Memantine. See all 11 dosages

  20 mg as needed daily 2 mg daily 20 mg weekly 5 mg daily 10 mg daily 15 mg daily 20 mg daily 40 mg daily 100 mg daily
  1 Number of Patients: 1 4 Number of Patients: 4 2 Number of Patients: 2 1 Number of Patients: 1 12 Number of Patients: 12 21 Number of Patients: 21 4 Number of Patients: 4 47 Number of Patients: 47 3 Number of Patients: 3 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Memantine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 13   Did not seem to work: 54%
Side effects too severe 5   Side effects too severe: 21%
Doctor's advice 4   Doctor's advice: 17%
Expense 3   Expense: 13%
Other 2   Other: 8%
Personal research 1   Personal research: 4%
Not indicated 1   Not indicated: 4%

See all 24 patients who’ve stopped taking Memantine

Currently Taking Memantine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Memantine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Memantine

Always
22 88%
Usually
1 4%
Sometimes
1 4%
Never
1 4%

Burden

Difficulty being on treatment

Burden of Memantine

Very
0 0%
Somewhat
0 0%
A little
6 24%
Not at all
19 76%

Cost

Paid out of pocket

Cost of Memantine

$200+
0 0%
$100-199
3 20%
$50-99
2 13%
$25-49
7 47%
< $25
3 20%

Report created on May 26, 2012.