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What is Tizanidine HCl?

Tizanidine hydrochloride is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Stiffness/Spasticity 589 110 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle spasms 296 72 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 143 24 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle pain 83 22 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Pain 70 19 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Muscle spasms in neck and shoulders 56 11 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 1313 patients currently taking Tizanidine HCl

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Reported Side Effects

Side effects as an overall problem

Severe
32
Moderate
71
Mild
80
None
93

Commonly reported side effects, conditions, and hospitalizations associated with Tizanidine HCl

Sleepiness 45
Dry mouth (xerostomia) 38
Dry eyes 19
Fatigue 18
Drowsiness 17
Excessive daytime sleepiness (somnolence) 10
See all 78 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Tizanidine HCl. See all 54 dosages

  daily 2mg as needed 4mg as needed 2 mg daily 4 mg daily 6 mg daily 8 mg daily 12 mg daily 16 mg daily 24 mg daily
  34 Number of Patients: 34 35 Number of Patients: 35 96 Number of Patients: 96 129 Number of Patients: 129 331 Number of Patients: 331 88 Number of Patients: 88 204 Number of Patients: 204 145 Number of Patients: 145 82 Number of Patients: 82 39 Number of Patients: 39  

Reported Stop Reasons

Why Patients Stopped Taking Tizanidine HCl (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 95   Did not seem to work: 40%
Side effects too severe 58   Side effects too severe: 24%
Other 51   Other: 21%
Doctor's advice 51   Doctor's advice: 21%
Personal research 12   Personal research: 5%
Course of treatment ended 11   Course of treatment ended: 5%
Expense 9   Expense: 4%
Change in health plan coverage 3   Change in health plan coverage: 1%
Not indicated 1   Not indicated: 0%

See all 236 patients who’ve stopped taking Tizanidine HCl

Currently Taking Tizanidine HCl

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Tizanidine HCl

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Tizanidine HCl

Always
181 66%
Usually
59 21%
Sometimes
27 10%
Never
9 3%

Burden

Difficulty being on treatment

Burden of Tizanidine HCl

Very
16 6%
Somewhat
16 6%
A little
47 17%
Not at all
197 71%

Cost

Paid out of pocket

Cost of Tizanidine HCl

$200+
1 1%
$100-199
0 0%
$50-99
11 6%
$25-49
23 12%
< $25
164 82%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.