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What is St. John's Wort?

St. John's wort, hypericum perforatum, is generally is used for depression, seasonal affective disorder, and anxiety. Products currently are standardized based on hypericin content, although the hyperforin and bioflavonoid contents are also believed responsible for activity.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Depressed mood 43 20 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 21 6 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Anxious mood 5 0
General health 5 2 Efficacy_slight Efficacy_none
Other 4 1 Efficacy_cant_tell
Major Depressive Disorder 3 2 Efficacy_moderate Efficacy_slight

See all 56 patients currently taking St. John's Wort

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Reported Side Effects

Side effects as an overall problem

Severe
1
Moderate
3
Mild
7
None
26

Reported Dosages

Frequently reported dosages based on patients currently taking St. John's Wort. See all 24 dosages

  daily as needed 2 tab(s) daily 4 daily 8 cap(s) daily 150 mg daily 300 mg daily 600 mg daily 900 mg daily 1,200 mg daily
  15 Number of Patients: 15 2 Number of Patients: 2 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 5 Number of Patients: 5 6 Number of Patients: 6 7 Number of Patients: 7 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking St. John's Wort (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 17   Did not seem to work: 35%
Other 17   Other: 35%
Doctor's advice 13   Doctor's advice: 27%
Personal research 7   Personal research: 15%
Side effects too severe 6   Side effects too severe: 13%
Course of treatment ended 6   Course of treatment ended: 13%
Expense 2   Expense: 4%
Not indicated 1   Not indicated: 2%

See all 48 patients who’ve stopped taking St. John's Wort

Currently Taking St. John's Wort

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking St. John's Wort

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of St. John's Wort

Always
25 68%
Usually
9 24%
Sometimes
2 5%
Never
1 3%

Burden

Difficulty being on treatment

Burden of St. John's Wort

Very
0 0%
Somewhat
2 5%
A little
7 19%
Not at all
28 76%

Cost

Paid out of pocket

Cost of St. John's Wort

$200+
0 0%
$100-199
0 0%
$50-99
0 0%
$25-49
4 15%
< $25
23 85%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.