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What is Mercaptopurine?

Mercaptopurine is an antineoplastic and immunosuppressant agent used for the treatment (maintenance and induction) of acute lymphoblastic leukemia. Off label it is used as a steroid-sparing agent for corticosteroid-dependent Crohn's disease and ulcerative colitis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Ulcerative colitis 7 4 Efficacy_major Efficacy_slight Efficacy_none Efficacy_cant_tell
Crohn's Disease 7 3 Efficacy_moderate Efficacy_cant_tell
MS (Multiple Sclerosis) 1 1 Efficacy_none

See all 16 patients currently taking Mercaptopurine

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 3
Mild
 1
None
 3

Commonly reported side effects, conditions, and hospitalizations associated with Mercaptopurine

Nausea 2
Body Aches 1
Thrombocytopenia (low platelet count) 1
Macrocytosis (large red blood cells) 1

Reported Dosages

  50 mg daily 75 mg daily 100 mg daily 125 mg daily 150 mg daily
  8 Number of Patients: 8 3 Number of Patients: 3 3 Number of Patients: 3 1 Number of Patients: 1 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Mercaptopurine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 1   Did not seem to work: 20%
Expense 1   Expense: 20%
Personal research 1   Personal research: 20%
Doctor's advice 1   Doctor's advice: 20%
Side effects too severe 1   Side effects too severe: 20%
Other 1   Other: 20%
Change in health plan coverage 1   Change in health plan coverage: 20%

See all 4 patients who’ve stopped taking Mercaptopurine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Mercaptopurine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking Mercaptopurine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Mercaptopurine

Always
 5 71%
Usually
 2 29%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Mercaptopurine

Very
 0 0%
Somewhat
 0 0%
A little
 3 43%
Not at all
 4 57%

Cost

Paid out of pocket

Cost of Mercaptopurine

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 0 0%
< $25
 2 100%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.