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What is Pyridostigmine?

Pyridostigmine is an acetylcholinesterase inhibitor used for the symptomatic treatment of myaesthenia gravis and as an antidote for nondepolarizing neuromuscular blockers.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Myasthenia Gravis 30 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 11 3 Efficacy_major Efficacy_moderate Efficacy_slight
Fatigue 7 2 Efficacy_moderate Efficacy_none
ALS (Amyotrophic Lateral Sclerosis) 4 0
Lambert-Eaton Myasthenic Syndrome 3 0
Dysautonomia 2 1 Efficacy_slight

See all 49 patients currently taking Pyridostigmine

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 6
Mild
 4
None
 8

Commonly reported side effects, conditions, and hospitalizations associated with Pyridostigmine

Diarrhea 2
Sweating 2
Nausea 1
Memory problems 1
Muscle twitching (fasciculations) 1
Phlegm 1
See all 12 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Pyridostigmine. See all 19 dosages ►

  60mg as needed 60 mg daily 80 mg daily 90 mg daily 120 mg daily 180 mg daily 240 mg daily 300 mg daily 360 mg daily 480 mg daily
  2 Number of Patients: 2 8 Number of Patients: 8 1 Number of Patients: 1 5 Number of Patients: 5 11 Number of Patients: 11 8 Number of Patients: 8 7 Number of Patients: 7 1 Number of Patients: 1 1 Number of Patients: 1 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Pyridostigmine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 8   Did not seem to work: 47%
Doctor's advice 5   Doctor's advice: 29%
Side effects too severe 3   Side effects too severe: 18%
Other 3   Other: 18%
Course of treatment ended 1   Course of treatment ended: 6%
Not indicated 1   Not indicated: 6%

See all 16 patients who’ve stopped taking Pyridostigmine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Pyridostigmine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Pyridostigmine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Pyridostigmine

Always
 9 50%
Usually
 6 33%
Sometimes
 2 11%
Never
 1 6%

Burden

Difficulty being on treatment

Burden of Pyridostigmine

Very
 0 0%
Somewhat
 1 6%
A little
 5 28%
Not at all
 12 67%

Cost

Paid out of pocket

Cost of Pyridostigmine

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 13%
$25-49
 3 38%
< $25
 4 50%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 26, 2012.