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What is Amantadine?

Amantadine is an antiviral medication that blocks actions of viruses. It is used to treat and prevent certain strains of influenza A. It is also used to treat Parkinson's Disease and "Parkinson-like" symptoms such as stiffness and shaking that may be caused by the use of certain drugs.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Parkinson's Disease 525 114 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fatigue 477 156 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Excessive daytime sleepiness (somnolence) 53 23 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 37 10 Efficacy_major Efficacy_moderate Efficacy_none Efficacy_cant_tell
Stiffness/Spasticity 36 6 Efficacy_major Efficacy_moderate Efficacy_slight
Tremor 33 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 958 patients currently taking Amantadine

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Reported Side Effects

Side effects as an overall problem

Severe
31
Moderate
56
Mild
60
None
201

Commonly reported side effects, conditions, and hospitalizations associated with Amantadine

Blotchy skin on my legs 12
Edema (fluid retention) 11
Constipation 11
General ill feeling 11
Fatigue 10
Dry mouth (xerostomia) 8
See all 113 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Amantadine. See all 38 dosages

  daily 100mg as needed 50 mg daily 50 mg/5 mL daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily 400 mg daily 600 mg daily
  23 Number of Patients: 23 12 Number of Patients: 12 3 Number of Patients: 3 3 Number of Patients: 3 271 Number of Patients: 271 4 Number of Patients: 4 409 Number of Patients: 409 167 Number of Patients: 167 34 Number of Patients: 34 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Amantadine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 213   Did not seem to work: 52%
Side effects too severe 108   Side effects too severe: 26%
Doctor's advice 81   Doctor's advice: 20%
Other 49   Other: 12%
Not indicated 12   Not indicated: 3%
Expense 11   Expense: 3%
Personal research 11   Personal research: 3%
Course of treatment ended 11   Course of treatment ended: 3%
Change in health plan coverage 2   Change in health plan coverage: 0%

See all 388 patients who’ve stopped taking Amantadine

Currently Taking Amantadine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Amantadine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Amantadine

Always
265 76%
Usually
51 15%
Sometimes
12 3%
Never
20 6%

Burden

Difficulty being on treatment

Burden of Amantadine

Very
9 3%
Somewhat
19 5%
A little
49 14%
Not at all
271 78%

Cost

Paid out of pocket

Cost of Amantadine

$200+
3 1%
$100-199
2 1%
$50-99
6 3%
$25-49
19 9%
< $25
192 86%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 23, 2012.