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What is Desvenlafaxine?

Desvenlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It is an extended release formulation believed to treat depression by affecting the levels of serotonin and norepinephrine, two neurotransmitters associated with depression.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Depressed mood 173 74 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Major Depressive Disorder 73 24 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Anxious mood 45 18 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Fibromyalgia 34 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Treat my mood condition(s) 31 15 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Bipolar Disorder 17 5 Efficacy_moderate Efficacy_slight Efficacy_none

See all 318 patients currently taking Desvenlafaxine

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Reported Side Effects

Side effects as an overall problem

Severe
32
Moderate
30
Mild
38
None
44

Commonly reported side effects, conditions, and hospitalizations associated with Desvenlafaxine

Nausea 13
Tiredness increased 12
Increased energy 12
Sedation 10
Sluggishness 9
Depressed mood 8
See all 83 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Desvenlafaxine. See all 13 dosages

  1 mg daily 1 other daily 2 mg daily 50 mg m,w,f 50 g daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily 200 mg daily
  5 Number of Patients: 5 2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 181 Number of Patients: 181 2 Number of Patients: 2 108 Number of Patients: 108 11 Number of Patients: 11 9 Number of Patients: 9  

Reported Stop Reasons

Why Patients Stopped Taking Desvenlafaxine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 50   Did not seem to work: 45%
Side effects too severe 41   Side effects too severe: 37%
Expense 22   Expense: 20%
Doctor's advice 20   Doctor's advice: 18%
Other 16   Other: 15%
Personal research 6   Personal research: 5%
Change in health plan coverage 4   Change in health plan coverage: 4%
Course of treatment ended 2   Course of treatment ended: 2%
Not indicated 1   Not indicated: 1%

See all 108 patients who’ve stopped taking Desvenlafaxine

Currently Taking Desvenlafaxine

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0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Desvenlafaxine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Desvenlafaxine

Always
121 84%
Usually
19 13%
Sometimes
2 1%
Never
2 1%

Burden

Difficulty being on treatment

Burden of Desvenlafaxine

Very
10 7%
Somewhat
12 8%
A little
17 12%
Not at all
105 73%

Cost

Paid out of pocket

Cost of Desvenlafaxine

$200+
3 3%
$100-199
5 5%
$50-99
19 20%
$25-49
29 31%
< $25
38 40%

Report created on May 25, 2012.