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What is Pramipexole?

Pramipexole is an anti-Parkinson's agent that is used to treat symptoms of Parkinson's Disease, such as stiffness, tremors, muscle spasms, and poor muscle control and for moderate to severe primary restless legs syndrome. Off label it is used for the treatment of depression.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Parkinson's Disease 678 209 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Restless feeling in legs 166 52 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
RLS (Restless Legs Syndrome) 73 12 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Tremor 50 29 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 45 7 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Stiffness/Spasticity 34 13 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_cant_tell

See all 1011 patients currently taking Pramipexole

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Reported Side Effects

Side effects as an overall problem

Severe
 71
Moderate
 101
Mild
 78
None
 103

Commonly reported side effects, conditions, and hospitalizations associated with Pramipexole

Drowsiness 77
Weight gain 43
Insomnia 35
Vivid dreams 29
Nausea 28
Forgetfulness 27
See all 154 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Pramipexole. See all 84 dosages ►

  0.125 mg daily 0.25 mg daily 0.375 mg daily 0.5 mg daily 0.75 mg daily 1 mg daily 1.5 mg daily 2 mg daily 3 mg daily 4.5 mg daily
  63 Number of Patients: 63 84 Number of Patients: 84 46 Number of Patients: 46 89 Number of Patients: 89 57 Number of Patients: 57 80 Number of Patients: 80 143 Number of Patients: 143 35 Number of Patients: 35 151 Number of Patients: 151 98 Number of Patients: 98  

Reported Stop Reasons

Why Patients Stopped Taking Pramipexole (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 161   Side effects too severe: 50%
Doctor's advice 90   Doctor's advice: 28%
Did not seem to work 81   Did not seem to work: 25%
Other 40   Other: 12%
Expense 24   Expense: 7%
Not indicated 17   Not indicated: 5%
Personal research 11   Personal research: 3%
Change in health plan coverage 8   Change in health plan coverage: 2%
Course of treatment ended 6   Course of treatment ended: 2%

See all 309 patients who’ve stopped taking Pramipexole

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Pramipexole

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Pramipexole

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Pramipexole

Always
 265 75%
Usually
 65 18%
Sometimes
 9 3%
Never
 14 4%

Burden

Difficulty being on treatment

Burden of Pramipexole

Very
 19 5%
Somewhat
 50 14%
A little
 72 20%
Not at all
 212 60%

Cost

Paid out of pocket

Cost of Pramipexole

$200+
 11 5%
$100-199
 11 5%
$50-99
 30 14%
$25-49
 53 24%
< $25
 115 52%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 25, 2012.