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What is Pregabalin?

Pregabalin is an analgesic and anti-convulsant drug that is used to manage pain associated with diabetic peripheral neuropathy, postherpetic (shingles) neuralgia, as an adjunctive treatment for partial-onset seizure disorder in adults and for the management of fibromyalgia.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose	# of patients	# of patients with evaluations Efficacy
Fibromyalgia	2816	900
Pain	662	200
Nerve pain (neuralgia)	403	137
Chronic Fatigue Syndrome	347	62
Numbness and Tingling with Pins and Needles	96	33
Other	93	18

See all 211 reasons taken ▼

See all 3150 patients currently taking Pregabalin

Mouse over the table for more information

Reported Side Effects

Side effects as an overall problem

Severe	400
Moderate	383
Mild	286
None	250

Commonly reported side effects, conditions, and hospitalizations associated with Pregabalin

See all 435 reported side effects ▼ See top 6 reported side effects ▲
Weight gain	309	309
Dizziness	143	143
Brain fog	134	134
Blurry vision	110	110
Daytime sleepiness	107	107
Lack of concentration	94	94
Tiredness	89	89
Increased fatigue	77	77
Slow to wake in morning	77	77
Headaches	54	54
Dry mouth (xerostomia)	30	30
Swelling in legs, feet and ankles	30	30
Drowsiness	28	28
Fatigue	25	25
Memory problems	23	23
Nausea	23	23
Excessive daytime sleepiness (somnolence)	23	23
Swelling in hands	18	18
Hospitalization	16	16
Constipation	13	13
Edema (fluid retention)	13	13
Swelling in feet	12	12
Problems concentrating	10	10
Dizziness (vertigo)	9	9
Anxious mood	9	9
Spaced out	9	9
Balance problems	9	9
Lightheadedness	8	8
Dry throat	8	8
Sleepiness	8	8
Fluid retention weight gain	8	8
Depressed mood	8	8
Swelling in ankles	7	7
Migraine headaches	7	7
Dizziness and feeling faint	7	7
High feeling	7	7
Rashes (redness, swelling)	6	6
Rapid weight gain	6	6
Drunk feeling	6	6
Insomnia	6	6
Vertigo	6	6
Increased appetite	6	6
Hallucinations	6	6
Irritability	5	5
Edema in lower extremities	5	5
Depression with suicidal thoughts	5	5
Stomach pain	5	5
Suicidal thoughts or urges	5	5
Muscle spasms	5	5
Sweating excessive	5	5
Memory and cognition problems	5	5
Abdominal bloating	4	4
Slurred speech	4	4
Itching (pruritus)	4	4
Sexual dysfunction	4	4
Memory lapses (brain blinks)	4	4
Diarrhea	4	4
Cognitive Confusion	4	4
Muscle twitching (fasciculations)	4	4
Loss of short term memory	4	4
Facial swelling	4	4
Groggy in morning	4	4
Pain in legs	4	4
Forgetfulness	4	4
Spinning dizziness (vertigo)	4	4
dizziness like jet lag, vagueness in my head with increasing intensity.	4	4
Water retention	4	4
Swelling in legs	4	4
Dizziness with nausea	3	3
Loss of balance	3	3
Shortness of breath (dyspnea)	3	3
Dry eyes	3	3
Heart palpitations	3	3
Pressure headaches	3	3
Mood changes	3	3
Swelling Generalized	3	3
Increased Hunger	3	3
Hands Tingling	3	3
Feel dopey	3	3
Craving carbs	3	3
Allergic reaction	3	3
Hair loss	3	3
Drowsy in a.m.	3	3
Shakiness	3	3
Hot flashes	3	3
Craving sweets sugar	3	3
Dizzy spells	3	3
weight gain,swelling in spinal area ,hands and feet	3	3
Excessive thirst (polydipsia)	3	3
Nausea and vomiting	3	3
Vision difficulty	3	3
Double vision (diplopia)	3	3
Chills/fever	3	3
Mood swings	3	3
Sedation	3	3
Off Balance	3	3
Tremor	3	3
Poor Concentration	3	3
Walking problems	3	3
Cramps in legs	3	3
Visual disturbance	3	3
Nerve pain (neuralgia)	2	2
In the beginning more so a off balance,drunk feeling,if awoke during the night and had to get up.	2	2
Gas	2	2
Abdominal cramps	2	2
Bump into things-walk like a drunk	2	2
Intermittent swelling of hands	2	2
Numbness in tongue	2	2
Drunk feeling when I increase dosage	2	2
Difficulty thinking	2	2
Breathing difficulty	2	2
Light sensitivity (photophobia)	2	2
Decreased appetite	2	2
Clumsiness	2	2
Exhaustion	2	2
Urinary retention	2	2
sleepy-loopy	2	2
Numbness and Tingling with Pins and Needles	2	2
Swollen tongue	2	2
Word finding difficulty	2	2
Pain in back of head	2	2
Heart rate increased	2	2
Pain	2	2
Numbness	2	2
Mentally dull	2	2
Edema in feet	2	2
Paresthesia	2	2
Excessive dry mouth	2	2
Jerky movements of hands	2	2
Dry skin	2	2
Mania	2	2
Tired eyes	2	2
Tremor in hands	2	2
Swelling in fingers	2	2
Constant brain fog	2	2
Tongue Tingling	2	2
Anxiety attacks	2	2
Edema in hands	2	2
Lightheadedness from upper back into head	2	2
Numbness in hands	2	2
Cognitive impairment	2	2
Memory Loss	2	2
Hearing problems	2	2
Muscle and joint pain	2	2
Major Depressive Disorder	2	2
Vision loss	2	2
Hives (urticaria)	2	2
Imbalance when walking	2	2
Excessive sleeping (hypersomnia)	2	2
Vomiting	2	2
Chronic Fatigue Syndrome	2	2
Racing heart feeling	2	2
Emotional numbness or flatness	2	2
Primary Insomnia	2	2
Pain and swelling on top of feet and toes	2	2
Unrefreshing or poor sleep	2	2
Dryness	2	2
Mental confusion	2	2
Sex drive (libido) decreased	2	2
Reactive Depression	2	2
Restless feeling in legs	2	2
Slowed thinking and comprehension	2	2
Difficulty urinating (dysuria)	2	2
Fibro fog	2	2
Fuzzy thinking	2	2
Feeling intoxicated	2	2
Skin rash	2	2
Auditory hallucinations	2	2
Flu like symptoms	2	2
Weakness in legs	2	2
Numbness in legs	2	2
Withdrawal effects	2	2
Nausea sometimes	2	2
Mean, Rude, Crazy, and Stubborn	2	2
Feeling of disconnection	2	2
Daytime tiredness	2	2
Stomach upset	2	2
Speech problems	2	2
Elevated blood pressure	2	2
Vision Abnormalities (Halos/Floaters/Snow)	2	2
Hard to get out of bed	2	2
Sleep problems	2	2
Anxiety and frustration	2	2
Withdrawal effects with missed dose	1	1
Auditory Processing Deficit	1	1
Vitamin D deficiency	1	1
GI problems	1	1
magnified symptoms	1	1
Sluggishness	1	1
Chronic Idiopathic Back Pain	1	1
Feeling out of it	1	1
Seizures (absence or petit mal)	1	1
Aggression	1	1
Irregular menstrual periods	1	1
Hostility	1	1
Feeling sick	1	1
Math Skills	1	1
Balance worsened	1	1
Calming	1	1
mild to moderate	1	1
Unsteadiness	1	1
Weird or strange dreams	1	1
Morning sleepiness	1	1
It made me lethargic (before I started the provigil)	1	1
Nosebleed(s)	1	1
Difficulty speaking (dysarthria)	1	1
Loss of focus	1	1
Dizziness upon moving	1	1
Numbness in lower extremities	1	1
Loopy feeling	1	1
Suicidal thoughts (emotionally backed)	1	1
Suicidal thoughts (free floating)	1	1
Jerky movements of arms	1	1
Gagging (throat spasm)	1	1
Intermittent urinary incontinence	1	1
doesnt help anything	1	1
Ringing in ears (tinnitus)	1	1
Skin Sensitivity	1	1
Swelling of throat and neck	1	1
Neurological Symptoms	1	1
Swelling of right foot	1	1
Water retention in hands and feet	1	1
Complete exhaustion	1	1
INCREASE ABDOMINAL GIRTH	1	1
Depression with anxiety	1	1
Sleep attacks (daytime)	1	1
Constant hunger	1	1
hard stools, gas	1	1
Zombification	1	1
suffocation	1	1
Body jerks	1	1
It feels like I'm wearing heavy socks and not wearing any.	1	1
Stumbling over words	1	1
Numbness in arms	1	1
Catastrophic thinking	1	1
Bradycardia	1	1
Loss of motor function	1	1
Serotonin syndrome	1	1
Worsening depression	1	1
repeating myself without realizing it in a converation	1	1
Swelling in lower legs	1	1
Nerve pain in arm	1	1
Increased or worsened depression	1	1
Generalized muscle aches	1	1
Bone Pain	1	1
Swollen lips	1	1
Constant extreme anger	1	1
Myoclonic jerking	1	1
Increase in widespread pain	1	1
Rash on face	1	1
Problems with focusing eyes	1	1
Occasional euphoria	1	1
Eye pressure	1	1
Listlessness	1	1
Mental fatigue or exhaustion	1	1
Frankenstein-like walk	1	1
Nighttime headache	1	1
Blisters	1	1
Fingers Tingling	1	1
Pitting edema	1	1
Migraine with aura	1	1
Large fluid filled blisters on face	1	1
Feel like a zombie	1	1
Falls with injury	1	1
Arms Tingling	1	1
Dizziness with disorientation	1	1
itching arms and all over upper torso	1	1
Suicide attempt	1	1
Legs Tingling worse when walking	1	1
Stupidity or "stupids" effect	1	1
Swollen feet	1	1
Heavy sensation in head	1	1
Pain in back of neck and shoulders	1	1
Extreme flu like malaise	1	1
Headaches with eye discomfort	1	1
always groggy, little energy. coordination problems, swolllen sore hands, very often disorientated, forgetful. dizzy	1	1
Bitter taste	1	1
Bladder irregularity	1	1
Occasional constipation	1	1
Chronic constipation	1	1
Fluid retention in lower extremities	1	1
Fears of cracking up or going crazy	1	1
drop foot and cramping/clubbing	1	1
Feeling better	1	1
Headaches which last for 5 days at a time	1	1
not getting asleep until 5am in the morning	1	1
Tired legs	1	1
Body Hair Loss	1	1
Altered state of consciousness	1	1
sore top of foot for 3 days having trouble walking	1	1
Swelling of the mouth	1	1
Swelling in the abdominal region	1	1
Head feels disconnected from rest of body	1	1
Increased pain	1	1
Bed wetting	1	1
Swelling in wrists	1	1
Stoned feeling	1	1
Blood Pressure Increased With Severe Pain	1	1
Feeling strange	1	1
Jerky movements of feet	1	1
Constant vomiting	1	1
Loss of bladder control	1	1
Pain in upper chest	1	1
Trouble holding things in left hand	1	1
Hangover effect in morning	1	1
Elevated CPK enzymes	1	1
Aching throbbing body	1	1
Inability to move	1	1
Tightness in throat and neck area	1	1
Weakness in thigh muscles	1	1
Feeling bad	1	1
Feeling out of body	1	1
Emotional lability	1	1
Loss of spatial awareness on right side	1	1
Rash or skin problems	1	1
Night sweats	1	1
Feeling of lump in throat	1	1
Eye pain	1	1
Deteriorating mental ability (dementia)	1	1
Difficulty sleeping through night	1	1
Fluid retention under the eyes	1	1
Burning sensation in soles of feet	1	1
Loss of sense of taste	1	1
Mouth sores (ulcers)	1	1
UTI symptoms	1	1
Vivid dreams	1	1
Pins and needles	1	1
Tightness in hands	1	1
Increased sensitivity sole of foot	1	1
Numbness in feet	1	1
Numbness in face	1	1
Shaky hands	1	1
Myoclonus	1	1
Elevated liver enzymes	1	1
Fasciculations in arms (twitching)	1	1
Muscle weakness	1	1
Aching burning throbbing body pain	1	1
Numbness in lips	1	1
Kidney Failure	1	1
Panic attacks	1	1
Night cramps in legs and feet	1	1
Suicidal	1	1
RLS (Restless Legs Syndrome)	1	1
Lethargy	1	1
Impulsive behaviors	1	1
Binge eating episodes	1	1
Tremor in legs	1	1
Neurological fatigue	1	1
Inability to concentrate	1	1
Lack of motivation	1	1
Feet Tingling	1	1
Peripheral edema	1	1
Eye Twitching	1	1
Stiffness	1	1
Spasms in jaw	1	1
Difficulty falling asleep	1	1
Muscle fatigue	1	1
Lips Tingling	1	1
Amnesia	1	1
Stumbling	1	1
Acne breakout	1	1
Confusion	1	1
Muscle cramps	1	1
Short term memory problems	1	1
Incontinence	1	1
Motion sickness	1	1
Tremulousness	1	1
Dizziness with hypotension upon standing	1	1
Weight loss	1	1
Obesity	1	1
Personality changes due to medication	1	1
Tachycardia (fast heart rate)	1	1
Fainting	1	1
Dreams exhausting	1	1
An overall crappy feeling all the time	1	1
Psychotic symptoms (anxiety depression fear)	1	1
Dehydration	1	1
Pessimism or negative attitude	1	1
Pain in hands	1	1
Difficulty with orgasm	1	1
Disoriented sense of time	1	1
Poor working memory	1	1
Temperature dysregulation	1	1
Feelings of isolation	1	1
Neck movement dizziness (Cervicogenic dizziness)	1	1
Throat tightening	1	1
Elevated blood sugar (hyperglycemia)	1	1
Somnolence	1	1
Hangover effect	1	1
Jittery feeling	1	1
Chills	1	1
Erectile Dysfunction	1	1
Mood elevated or improved	1	1
Ataxia (lack of coordination)	1	1
Appetite change	1	1
Loss of sex drive (libido)	1	1
Head pressure	1	1
Dropping things	1	1
Laziness	1	1
Sickness	1	1
Moodiness	1	1
Daytime sedation	1	1
Crying spells	1	1
Paresthesia in lower extremeties	1	1
Unsteady gait	1	1
Kidney stone	1	1
Edema of extremities	1	1
Coordination problems with use	1	1
slowed reaction time	1	1
Slowed thinking	1	1
Stiffness in neck	1	1
Urinary problems	1	1
Personality change	1	1
Acid reflux	1	1
Dry hair	1	1
Druggy buzz	1	1
Abnormal thoughts	1	1
Awkward taste in food	1	1
Allergies	1	1
Jerky movements (dyskinesia)	1	1
Slowness	1	1
Irrational behavior	1	1
Loss of appetite	1	1
Vaginal dryness	1	1
Bowel problems	1	1
Bladder problems	1	1
Blood pressure raised dangerously high	1	1
Numbness in fingers	1	1
Bloating	1	1
Stabbing pain	1	1
Dry mouth at night	1	1
Low blood pressure	1	1
Problems with coordination	1	1
Dry Eye Syndrome	1	1
got lost while driving	1	1

Reported Dosages

Frequently reported dosages based on patients currently taking Pregabalin. See all 78 dosages ►

50 mg daily	75 mg daily	100 mg daily	150 mg daily	200 mg daily	225 mg daily	300 mg daily	400 mg daily	450 mg daily	600 mg daily
242	257	263	702	217	179	695	104	252	180

Reported Stop Reasons

Why Patients Stopped Taking Pregabalin (multiple reasons could be selected)
Reason	# Patients	Percentage of patients
Side effects too severe	1038
Did not seem to work	718
Doctor's advice	234
Expense	226
Other	159
Change in health plan coverage	63
Personal research	59
Course of treatment ended	36
Not indicated	30

See all 1715 patients who’ve stopped taking Pregabalin

Reported Duration See details about how long patients take this treatment ▼ Reported Duration Hide details ▲

Currently Taking Pregabalin

A bar graph

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
21	45	77	121	166	545

Stopped Taking Pregabalin

A bar graph

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
333	379	255	308	210	164

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Pregabalin

Always	1035	78%
Usually	172	13%
Sometimes	37	3%
Never	75	6%

Burden

Difficulty being on treatment

Burden of Pregabalin

Very	123	9%
Somewhat	171	13%
A little	192	15%
Not at all	833	63%

Cost

Paid out of pocket

Cost of Pregabalin

$200+	23	3%
$100-199	78	9%
$50-99	167	19%
$25-49	250	28%
< $25	359	41%

See more information, including instructions, precautions, side effects, and interactions.

Patient Evaluations

See all 1319 patient evaluations

Brensui

Sex: F

Pain: All

Fatigue: All

Sleep: All

Stiffness: All

function: None

external_stress: Most

Stickman: all
Description:F44y
FM:4y Dx
Brensui

150 mg daily

since Dec 09, 2008
Efficacy Moderate for Fibromyalgia
Side Effects None
Advice/Tips Start out at a low dose and work your way up. Try to stay on the lowest dose possible that will help control your pain. If you need to use during the day, us... See full evaluation

envyjoy

Sex: F

Pain: Most

Fatigue: Most

Sleep: All

Stiffness: All

function: Most

external_stress: Some

Stickman: all
Description:F26y
FM:5y Dx
envyjoy

150 mg daily

since Jun 01, 2010
Efficacy Major for Fibromyalgia
Side Effects Mild
See full evaluation

poshbird

Sex: F

Pain: Some

Fatigue: Some

Sleep: Some

Stiffness: Most

function: Some

external_stress: Some

Stickman: most
Description:F49y
CFS:?y Dx
FM:3y Dx
poshbird

150 mg daily

since Jun 21, 2010
Efficacy Slight for Fibromyalgia
Side Effects Mild
Advice/Tips i would be very careful going too high on doseage, i was ok on 75mg x 3 times a day, but when i went up to 100 mg x 3 daily, i actually felt worse than befor... See full evaluation

See all 1319 patient evaluations

Report created on May 25, 2012.

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Pregabalin Treatment Report

What is Pregabalin?

Reported Purpose & Efficacy

Reported Side Effects

Reported Dosages

Reported Stop Reasons

Reported Duration See details about how long patients take this treatment ▼ Reported Duration Hide details ▲

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Patient Evaluations

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Pregabalin Treatment Report

What is Pregabalin?

Reported Purpose & Efficacy

Reported Side Effects

Reported Dosages

Reported Stop Reasons

Reported Duration See details about how long patients take this treatment ▼ Reported Duration Hide details ▲

Reported Adherence, Burden & Cost See details from patient evaluations ▼ Reported Adherence, Burden & Cost Hide details ▲

Patient Evaluations

See all 1319 patient evaluations

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Reported Adherence, Burden & Cost See details from patient evaluations ▼