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What is Duloxetine?

Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI). It is used for depression, general anxiety disorder, pain associated with diabetic neuropathy and for fibromyalgia.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Fibromyalgia 2951 958 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Depressed mood 1290 441 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Major Depressive Disorder 608 121 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Pain 427 142 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Chronic Fatigue Syndrome 398 46 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Generalized Anxiety Disorder 312 72 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 4011 patients currently taking Duloxetine

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Reported Side Effects

Side effects as an overall problem

Severe
 371
Moderate
 367
Mild
 423
None
 473

Commonly reported side effects, conditions, and hospitalizations associated with Duloxetine

Nausea 137
Sex drive (libido) decreased 125
Dizziness 100
Sweating increased 97
Weight gain 91
Insomnia 78
See all 432 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Duloxetine. See all 59 dosages ►

  daily 20 mg daily 30 mg daily 40 mg daily 50 mg daily 60 mg daily 80 mg daily 90 mg daily 120 mg daily 180 mg daily
  16 Number of Patients: 16 242 Number of Patients: 242 713 Number of Patients: 713 79 Number of Patients: 79 8 Number of Patients: 8 2254 Number of Patients: 2254 8 Number of Patients: 8 343 Number of Patients: 343 585 Number of Patients: 585 16 Number of Patients: 16  

Reported Stop Reasons

Why Patients Stopped Taking Duloxetine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 955   Side effects too severe: 48%
Did not seem to work 776   Did not seem to work: 39%
Doctor's advice 284   Doctor's advice: 14%
Expense 258   Expense: 13%
Other 233   Other: 12%
Personal research 74   Personal research: 4%
Change in health plan coverage 74   Change in health plan coverage: 4%
Course of treatment ended 34   Course of treatment ended: 2%
Not indicated 22   Not indicated: 1%

See all 1850 patients who’ve stopped taking Duloxetine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Duloxetine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Duloxetine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Duloxetine

Always
 1391 85%
Usually
 156 10%
Sometimes
 19 1%
Never
 68 4%

Burden

Difficulty being on treatment

Burden of Duloxetine

Very
 118 7%
Somewhat
 148 9%
A little
 212 13%
Not at all
 1156 71%

Cost

Paid out of pocket

Cost of Duloxetine

$200+
 30 3%
$100-199
 92 8%
$50-99
 200 18%
$25-49
 333 30%
< $25
 441 40%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 25, 2012.