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What is Desipramine?

Desipramine is a tricyclic antidepressant (TCA) that inhibits the reuptake of norepinephrine. It is sold under the brand names Norpramin® and Pertofrane®. It is used to treat depression, neuropathic pain, and ADHD.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Nerve pain (neuralgia) 10 3 Efficacy_moderate Efficacy_slight Efficacy_cant_tell
Depressed mood 7 4 Efficacy_major Efficacy_moderate Efficacy_none
Treat my mood condition(s) 5 2 Efficacy_none Efficacy_cant_tell
Sleep problems 5 0
Pain 4 0
Major Depressive Disorder 3 1 Efficacy_moderate

See all 35 patients currently taking Desipramine

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Reported Side Effects

Side effects as an overall problem

Severe
 2
Moderate
 3
Mild
 2
None
 5

Commonly reported side effects, conditions, and hospitalizations associated with Desipramine

Dry mouth at night 2
Fatigue 1
Dry mouth (xerostomia) 1
Elevated blood pressure 1
Sweating excessive 1
Tachycardia (fast heart rate) 1
See all 12 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Desipramine. See all 14 dosages ►

  10 mg daily 20 mg daily 30 mg daily 50 mg daily 75 mg daily 85 mg daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily
  3 Number of Patients: 3 4 Number of Patients: 4 1 Number of Patients: 1 11 Number of Patients: 11 3 Number of Patients: 3 1 Number of Patients: 1 2 Number of Patients: 2 3 Number of Patients: 3 2 Number of Patients: 2 3 Number of Patients: 3  

Reported Stop Reasons

Why Patients Stopped Taking Desipramine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 6   Did not seem to work: 38%
Doctor's advice 6   Doctor's advice: 38%
Side effects too severe 6   Side effects too severe: 38%
Personal research 1   Personal research: 6%
Other 1   Other: 6%
Course of treatment ended 1   Course of treatment ended: 6%

See all 15 patients who’ve stopped taking Desipramine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Desipramine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Desipramine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Desipramine

Always
 8 67%
Usually
 3 25%
Sometimes
 1 8%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Desipramine

Very
 0 0%
Somewhat
 1 8%
A little
 3 25%
Not at all
 8 67%

Cost

Paid out of pocket

Cost of Desipramine

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 14%
$25-49
 0 0%
< $25
 6 86%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 25, 2012.