What is PLS?
Primary lateral sclerosis (PLS) is a rare neuromuscular disease characterized by progressive muscle weakness in the voluntary muscles. PLS belongs to a group of disorders known as motor neuron diseases.
What is it like to have PLS?
| Common Symptoms | Patients' Latest Severity | My Current Severity |
|---|---|---|
|
||
| Anxious mood | None Mild Moderate Severe | |
| Constipation | None Mild Moderate Severe | |
| Emotional lability | None Mild Moderate Severe | |
| Excess saliva | None Mild Moderate Severe | |
| Excessive yawning | None Mild Moderate Severe | |
| Fasciculations | None Mild Moderate Severe | |
| Stiffness/Spasticity | None Mild Moderate Severe |
What do patients take to treat PLS and its symptoms?
Commonly prescribed and frequently used treatments
| Treatment name | Efficacy | Overall rating of side effects | # of Evaluations |
|---|---|---|---|
|
Baclofen
(Kemstro, DOM-Baclofen, Gabalon, Spinax)
|
12 | ||
|
Riluzole
(Rilutek)
|
6 |
These charts show data from PLS patients' latest treatment evaluations
Who has PLS at PatientsLikeMe?
- 387 patients have this condition
- 2 New patients joined this month
- 372 say PLS is their primary condition
| <20 | 20-29 | 30-39 | 40-49 | 50-59 | 60-69 | 70+ |
|---|---|---|---|---|---|---|
| Current Age | ||||||
| Gender | |
| 58% | Females |
|---|---|
| 42% | Males |
| Age at first symptom | # of patients | Proportion |
|---|---|---|
| 0-19 yrs | 3 | |
| 20-29 yrs | 12 | |
| 30-39 yrs | 42 | |
| 40-49 yrs | 69 | |
| 50-59 yrs | 77 | |
| 60-69 yrs | 26 | |
| 70+ yrs | 3 |
| Diagnosis status | # of patients | Proportion |
|---|---|---|
| Diagnosed | 197 | |
| Not Officially Diagnosed | 63 |
These charts show data from PLS patients who have completed their condition history