Major Depressive Disorder

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What is Major Depressive Disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

What is it like to have Major Depressive Disorder?

Common symptoms How bad it is What people are taking for it
Amphetamine-Dextroamphetamine, Modafinil, Methylphenidate
Individual Therapy, Amphetamine-Dextroamphetamine, Lisdexamfetamine
Methylphenidate, Lisdexamfetamine, Amphetamine-Dextroamphetamine
Bupropion, Citalopram, Fluoxetine
Venlafaxine, Amphetamine-Dextroamphetamine, Duloxetine
Individual Therapy, Positive self-talk, Work
Clonazepam, Alprazolam, Lorazepam
Ibuprofen, Acetaminophen (Paracetamol), Topiramate
Trazodone, Zolpidem, Quetiapine
Cyclobenzaprine, Massage Therapy, Clonazepam
Promethazine, Ondansetron, Metoclopramide
Hydrocodone, Ibuprofen, Lidocaine Transdermal
Scopolamine, Omeprazole OTC, Pantoprazole
Tramadol, Hydrocodone-Acetaminophen, Gabapentin
Meclizine, CT Scan Head, Meclizine Prescription
Alprazolam, Meditation, Clonazepam

What do patients take to treat Major Depressive Disorder and its symptoms?

Treatments reported by members Perceived effectiveness Overall rating of side effects # of Evaluations

(Psychosexual therapy, Psychiatrist and Psychologist, Integrative Counselling, Licensed Social Worker)


(Forfivo XL, Bupropion SR, Voxra, Novo-Bupropion)


(Venlalic XL, Zarelis, Venlor XR, Novo-Venlafaxine XR)


(Yentreve, Cymgen, Yelate, Cymbalta)


(Nuzak, Flunil, Zactin, Nopres)


(Ran-Citalo, Depramil, Citalec, Co-Citalopram)


(Gladem, Serdep, Apo-Sertraline, Altruline)


(Pramatis, Es Pramcit, Loxalate, Esopram)


(ADCO Mirteron, Avanza, Mirzaten, Rexer)




(Bilateral Electroconvulsive Therapy ECT, Unilateral Electroconvulsive Therapy ECT, Bifrontal Electroconvulsive Therapy ECT)


(Zedan, Amirozole, Abilify Discmelt, Abilify)


(Lamictal Starter Kit (Orange), Lamictin, Lamictal Green, Lamogine)




(Ratio-Quetiapine, Dopaquel, Ketipinor, Cobalt-Quetiapine)


These charts show data from Major Depressive Disorder patients’ latest treatment evaluations
Last updated:

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has Major Depressive Disorder on PatientsLikeMe?

  • 15,016 patients have this condition
  • 66 new patients joined this month
  • 5,506 say Major Depressive Disorder is their primary condition

Age Proportion # of patients
<20 272
20s 2,428
30s 3,241
40s 3,609
50s 2,832
60s 987
70+ 134


Distribution of females vs. males

78% Females
22% Males
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 3,548
20-29 years 1,409
30-39 years 938
40-49 years 506
50-59 years 154
60-69 years 16
70+ years 3

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 10,405
Not Diagnosed 1,962

These charts show data from Major Depressive Disorder patients who have completed their condition history
Last updated: