Major Depressive Disorder

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What is Major Depressive Disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

Common symptoms reported by people with Major Depressive Disorder

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

Treatments taken by people with Major Depressive Disorder

You’ve tried
Treatment name(s)
Type
How many have tried
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
Type
Prescription Drug
How many have tried
553
Tried for
Major Depressive Disorder (498) Depressed mood (123)
6 more
Check to add this treatment to your profile
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
Type
Prescription Drug
How many have tried
535
Tried for
Major Depressive Disorder (486) Depressed mood (98)
6 more
Check to add this treatment to your profile
Treatment name(s)
Type
Psychotherapy
How many have tried
468
Tried for
Major Depressive Disorder (462) Depressed mood (11)
6 more
Check to add this treatment to your profile
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
Type
Prescription Drug
How many have tried
435
Tried for
Major Depressive Disorder (398) Depressed mood (85)
6 more
Check to add this treatment to your profile
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
Type
Prescription Drug
How many have tried
427
Tried for
Major Depressive Disorder (383) Depressed mood (89)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
Type
Prescription Drug
How many have tried
399
Tried for
Major Depressive Disorder (355) Depressed mood (88)
5 more
Check to add this treatment to your profile
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
Type
Prescription Drug
How many have tried
395
Tried for
Major Depressive Disorder (372) Depressed mood (74)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
Type
Prescription Drug
How many have tried
284
Tried for
Major Depressive Disorder (243) Depressed mood (63)
3 more
Check to add this treatment to your profile
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
Type
Prescription Drug
How many have tried
242
Tried for
Anxious mood (220) Insomnia (25)
5 more
Check to add this treatment to your profile
Treatment name(s)

(Conzip, Dolol, Dolzam) 23 more
Type
Prescription Drug
How many have tried
160
Tried for
Pain (155) Back pain (11)
3 more

Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments taken by people with Major Depressive Disorder

You’ve tried
Treatment name(s)
Perceived effectiveness
Side effects
How many evaluations
Tried for
Check to add this treatment to your profile
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
Perceived effectiveness
for Major Depressive Disorder (186 evaluations)
Side effects
Nausea Weight gain 125 more
How many evaluations
293
Tried for
Major Depressive Disorder (498) Depressed mood (123)
6 more
Check to add this treatment to your profile
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
Perceived effectiveness
for Major Depressive Disorder (206 evaluations)
Side effects
Anxious mood Nausea 113 more
How many evaluations
282
Tried for
Major Depressive Disorder (486) Depressed mood (98)
6 more
Check to add this treatment to your profile
Treatment name(s)
Perceived effectiveness
for Major Depressive Disorder (102 evaluations)
Side effects
Anxious mood Anger 17 more
How many evaluations
129
Tried for
Major Depressive Disorder (462) Depressed mood (11)
6 more
Check to add this treatment to your profile
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
Perceived effectiveness
for Major Depressive Disorder (170 evaluations)
Side effects
Weight gain Fatigue 118 more
How many evaluations
219
Tried for
Major Depressive Disorder (398) Depressed mood (85)
6 more
Check to add this treatment to your profile
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
Perceived effectiveness
for Major Depressive Disorder (172 evaluations)
Side effects
Dry mouth Sex drive (libido) decreased 89 more
How many evaluations
230
Tried for
Major Depressive Disorder (383) Depressed mood (89)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
Perceived effectiveness
for Major Depressive Disorder (141 evaluations)
Side effects
Nausea Vivid dreams 101 more
How many evaluations
207
Tried for
Major Depressive Disorder (355) Depressed mood (88)
5 more
Check to add this treatment to your profile
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
Perceived effectiveness
for Major Depressive Disorder (153 evaluations)
Side effects
Dry mouth Weight gain 111 more
How many evaluations
191
Tried for
Major Depressive Disorder (372) Depressed mood (74)
3 more
Check to add this treatment to your profile
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
Perceived effectiveness
for Major Depressive Disorder (110 evaluations)
Side effects
Weight gain Sex drive (libido) decreased 76 more
How many evaluations
160
Tried for
Major Depressive Disorder (243) Depressed mood (63)
3 more
Check to add this treatment to your profile
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
Perceived effectiveness
for Anxious mood (105 evaluations)
Side effects
Drowsiness Sleepiness 40 more
How many evaluations
133
Tried for
Anxious mood (220) Insomnia (25)
5 more
Check to add this treatment to your profile
Treatment name(s)

(Conzip, Dolol, Dolzam) 23 more
Perceived effectiveness
for Pain (62 evaluations)
Side effects
Dizziness Nausea 28 more
How many evaluations
65
Tried for
Pain (155) Back pain (11)
3 more

Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has Major Depressive Disorder on PatientsLikeMe?


Age
Age Proportion # of patients
<20 228
20s 2,402
30s 3,472
40s 3,961
50s 3,294
60s 1,274
70+ 180

Gender

Distribution of females vs. males

77% Females
23% Males
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 3,877
20-29 years 1,537
30-39 years 1,039
40-49 years 561
50-59 years 186
60-69 years 18
70+ years 2

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 11,085
Not Diagnosed 1,960

These charts show data from Major Depressive Disorder patients who have completed their condition history
Last updated: