Major Depressive Disorder

We’re all in this for good.

By sharing your stories and data, you will:
  • help each other live better and uncover the best ways to manage your health today
  • help researchers shorten the path to new treatments tomorrow

How much good can your data do? A whole lot, as co-founder Jamie Heywood explains in this video.

What is Major Depressive Disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

What is it like to have Major Depressive Disorder?

Common symptoms
How bad it is
What people are taking for it

Reports may be affected by other conditions and/or medication side effects. We ask about general symptoms (anxious mood, depressed mood, insomnia, fatigue, and pain) regardless of condition.
Last updated:

What do patients take to treat Major Depressive Disorder and its symptoms?

You’ve tried
Treatment name(s)
Type
How many have tried
How many evaluations
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
Type
Prescription Drug
How many have tried
567
How many evaluations
311
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
Type
Prescription Drug
How many have tried
534
How many evaluations
283
Treatment name(s)
Type
Psychotherapy
How many have tried
473
How many evaluations
133
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
Type
Prescription Drug
How many have tried
444
How many evaluations
218
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
Type
Prescription Drug
How many have tried
435
How many evaluations
240
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
Type
Prescription Drug
How many have tried
406
How many evaluations
217
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
Type
Prescription Drug
How many have tried
405
How many evaluations
193
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
Type
Prescription Drug
How many have tried
285
How many evaluations
158
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
Type
Prescription Drug
How many have tried
245
How many evaluations
135
Treatment name(s)

(Cobalt-Quetiapine, Dopaquel, Ketipinor) 4 more
Type
Prescription Drug
How many have tried
167
How many evaluations
90
See all 761 treatments
Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

Compare treatments for Major Depressive Disorder

You’ve tried
Treatment name(s)
How many have tried
Perceived effectiveness
Side effects
How many evaluations
Treatment name(s)

(Cymbalta, Cymgen, Yelate) 1 more
How many have tried
567
Perceived effectiveness
Side effects
Nausea Weight gain 131 more
How many evaluations
311
Treatment name(s)

(Aplenzin, Budeprion SR, Budeprion XL) 12 more
How many have tried
534
Perceived effectiveness
Side effects
Nausea Anxious mood 112 more
How many evaluations
283
Treatment name(s)
How many have tried
473
Perceived effectiveness
Side effects
Anxious mood Anger 17 more
How many evaluations
133
Treatment name(s)

(Altruline, Apo-Sertraline, Daxid) 11 more
How many have tried
444
Perceived effectiveness
Side effects
Weight gain Fatigue 118 more
How many evaluations
218
Treatment name(s)

(APO-Citalopram, Alcytan, Celexa) 15 more
How many have tried
435
Perceived effectiveness
Side effects
Sex drive (libido) decreased Difficulty with orgasm 89 more
How many evaluations
240
Treatment name(s)

(Actan, Flunil, Fluxene) 15 more
How many have tried
406
Perceived effectiveness
Side effects
Nausea Vivid dreams 101 more
How many evaluations
217
Treatment name(s)

(Effexor, Effexor XR, Novo-Venlafaxine XR) 9 more
How many have tried
405
Perceived effectiveness
Side effects
Dry mouth Weight gain 112 more
How many evaluations
193
Treatment name(s)

(Cipralex, Es Pramcit, Esipram) 6 more
How many have tried
285
Perceived effectiveness
Side effects
Weight gain Sex drive (libido) decreased 75 more
How many evaluations
158
Treatment name(s)

(APO Clonazepam, Clonex, Clonotril) 7 more
How many have tried
245
Perceived effectiveness
Side effects
Drowsiness Sleepiness 41 more
How many evaluations
135
Treatment name(s)

(Cobalt-Quetiapine, Dopaquel, Ketipinor) 4 more
How many have tried
167
Perceived effectiveness
Side effects
Weight gain Excessive daytime sleepiness (somnolence) 49 more
How many evaluations
90
See all 761 treatments
Data from patients with Major Depressive Disorder, who reported starting treatments within the last 5 years.
Last updated:
You’ve tried this treatment.

  • Major
  • Moderate
  • Slight
  • None
  • Can't tell
  • Severe
  • Moderate
  • Mild
  • None

Who has Major Depressive Disorder on PatientsLikeMe?


Age
Age Proportion # of patients
<20 233
20s 2,392
30s 3,425
40s 3,911
50s 3,246
60s 1,236
70+ 175

Gender

Distribution of females vs. males

78% Females
22% Males
Age at first symptom
Age at first symptom Proportion # of patients
0-19 years 3,848
20-29 years 1,527
30-39 years 1,025
40-49 years 555
50-59 years 186
60-69 years 18
70+ years 2

Diagnosis status
Diagnosis status Proportion # of patients
Diagnosed 11,020
Not Diagnosed 1,958

These charts show data from Major Depressive Disorder patients who have completed their condition history
Last updated: