What is Major Depressive Disorder?

Major depressive disorder, also known as clinical depression, is marked by depressed mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and may include thoughts of suicide.

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What is it like to have Major Depressive Disorder?

Common symptoms How bad it is What people are taking for it
Severity
Severe
Moderate
Mild
None
Dextroamphetamine, Lisdexamfetamine, Amphetamine-Dextroamphetamine
Amphetamine-Dextroamphetamine, Modafinil, Methylphenidate
Methylphenidate, Lisdexamfetamine, Amphetamine-Dextroamphetamine
Bupropion, Fluoxetine, Citalopram
Zolpidem, Trazodone, Quetiapine
Ibuprofen, Acetaminophen (Paracetamol), Topiramate
Individual Therapy, Work, Positive self-talk
Amphetamine-Dextroamphetamine, Sertraline, Dextroamphetamine
Clonazepam, Alprazolam, Lorazepam
Cyclobenzaprine, Massage Therapy, Clonazepam
Hydrocodone, Ibuprofen, Hydrocodone-Acetaminophen
Hydrocodone-Acetaminophen, Tramadol, Ibuprofen
Pantoprazole, Omeprazole, Omeprazole OTC
Promethazine, Ondansetron, Metoclopramide
Meclizine Prescription, Prochlorperazine, Meclizine
Alprazolam, Meditation, Clonazepam

What do patients take to treat Major Depressive Disorder and its symptoms?

Treatments reported by members Perceived effectiveness Overall rating of side effects # of Evaluations
(Psychosexual therapy, Sex therapy, Narrative therapy, Integrative Counselling)
216
(Wellbutrin SR, Budeprion SR, Zetron, Elontril)
208
(ViePax XL, Venlor XR, Effexor, Zarelis)
192
(Yentreve, Cymbalta)
171
(Seronil, Flunil, Moltoben, Prozac)
164
(Dr. Reddy's Lab Citalopram, Co-Citalopram, Citabax, Seropram)
148
(Gladem, Sertral, Altruline, Mylan-Sertraline)
138
(Esopram, Lexamil, Seroplex, Esipram)
93
(Pristiq)
32
(Remeron SolTab, Axit, Avanza, Zispin)
31
(Bilateral Electroconvulsive Therapy ECT, Unilateral Electroconvulsive Therapy ECT, Bifrontal Electroconvulsive Therapy ECT)
25
(Zedan, Abilify, Amirozole)
24
(Lamictal ODT, Lamogine, Lamictal XR, Lamictal Starter Kit (Orange))
22
(Quilonum SR, Lithosun, Carbolithium, Eskalith CR)
17
(Viibryd)
11

These charts show data from Major Depressive Disorder patients' latest treatment evaluations

Who has Major Depressive Disorder at PatientsLikeMe?

<20 20s 30s 40s 50s 60s 70+
Current Age
Distribution of females vs. males
Gender
78% Females
22% Males
Age at first symptom
Age at first symptom # of patients Proportion
0-19 years 3,118
20-29 years 1,240
30-39 years 819
40-49 years 449
50-59 years 121
60-69 years 11
70+ years 3
Diagnosis status
Diagnosis status # of patients Proportion
Not Diagnosed 1,891
Diagnosed 9,527

These charts show data from Major Depressive Disorder patients who have completed their condition history