Eligibility

Ages Eligible for Study

21 years to 55 years

Genders Eligible for Study

Both

Keywords

Naltrexone, problem drinking, medication adherence, adherence, and smartphone

Sponsors

NIH

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Industry

Talaria, Inc

Inclusion Criteria

- problem or heavy drinkers

- age 21-55 years old

- located in the greater Albuquerque NM area

- interested in either reducing or stopping their drinking

- candidates for naltrexone pharmacotherapy

Exclusion Criteria

- participation in other naltrexone study

- unable to operate a smartphone

- significant psychiatric or physical illness

- current drug dependence

- current regular opioid use

- any recent nonmedical opioid use

- any lifetime opioid dependence

Detailed Description

Talaria, Inc., has designed an adherence tracking and enhancement system, called AGATE, which uses the text messaging and internet capabilities of modern cellular phones to address the problem of medication adherence in clinical care and clinical trial contexts. This trial will evaluate whether AGATE improves medication adherence in the context of a pharmacotherapy trial of naltrexone to treat problem drinking. All participants will be treatment-seeking problem drinkers who will receive naltrexone and medication monitoring over 8 weeks.