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Home > Research > Clinical Trials > Timing of Orthopaedic Surgery in the Multiply-injured Patient: Development of a Protocol for Early Appropriate Care. Clinical trial #NCT00888160
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Timing of Orthopaedic Surgery in the Multiply-injured Patient: Development of a Protocol for Early Appropriate Care

Conditions Phase Intervention Type
  • Fractures, Bone
  • Femoral Fractures
N/A

View trial NCT00888160 on www.clinicaltrials.gov

No PatientsLikeMe members are eligible for this trial.

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Contacts

Please use the information below to contact the trial coordinators.

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Eligibility

Ages Eligible for Study
16 years and up
Genders Eligible for Study
Both

Keywords

Sponsors

Other
MetroHealth Medical Center

Inclusion Criteria

- All patients at least 16 years of age treated at a major urban level 1 trauma center
between the years 2000 and 2006, who had any of the following musculoskeletal
injuries:

- unstable pelvic ring fracture

- unstable acetabulum fracture, or

- femur fracture

- Patients will be included regardless of race or gender. Isolated fractures will be
included

Exclusion Criteria

- Low-energy pelvis and hip fractures will be excluded

- Patients younger than 16 years of age will be excluded

Detailed Description

Early fixation of unstable fractures of the femur, pelvis, and acetabulum reduces some complication rates. However, in patients with multiple injuries, the optimal treatment of skeletal trauma may be affected by severe injury to the head, chest, or abdomen. The relationship between associated injury severity and the timing of definitive management of unstable fractures is not well-understood. The practice of "early total care," early definitive fracture management, has been criticized by some, who have suggested that additional hemorrhage with surgery may be associated with a deleterious systemic inflammatory response. The alternative extreme of "damage control orthopedics (DCO)" has been recently proposed as a means of providing provisional stability of major skeletal injury, generally through external fixation. It is speculated that DCO will diminish the potential for systemic compromise. However, the need for further (definitive) surgery on a delayed basis, and the potential additional complications and costs associated with this strategy are controversial. The investigators' goals are to define which injuries or parameters warrant delay of definitive orthopaedic care, and to determine what time interval for fracture fixation promotes optimal patient outcome. The investigators will assess the effects of fracture fixation on head injury, chest injury, abdominal injury, mortality, complications, patient outcomes, and costs.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00888160

Locations

  • MetroHealth Medical Center
    Cleveland, Ohio United States
    (Recruiting)

    Contact info

    Alysse Boyd, M.A.
    216-778-3657
    aboyd1@metrohealth.org

Learn more at ClinicalTrials.gov

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