Dasatinib in Treating Patients With Recurrent or Metastatic Malignant Salivary Gland Tumors

Conditions Phase Intervention Type
  • Carcinoma, Adenoid Cystic
  • Head and Neck Neoplasms
  • Salivary Gland Diseases
  • Salivary Gland Neoplasms
Phase 2
Drug
dasatinib
Genetic
gene expression analysis
Genetic
gene rearrangement analysis
Genetic
mutation analysis
Genetic
polymerase chain reaction
Genetic
polymorphism analysis
Other
immunohistochemistry staining method
Other
laboratory biomarker analysis
Other
pharmacogenomic studies

View trial NCT00859937 on www.clinicaltrials.gov

Eligibility

Ages Eligible for Study
18 years and up
Genders Eligible for Study
Both

Keywords

stage IV salivary gland cancer, recurrent salivary gland cancer, salivary gland adenoid cystic carcinoma, high-grade salivary gland mucoepidermoid carcinoma, salivary gland adenocarcinoma, salivary gland anaplastic carcinoma, salivary gland malignant mixed cell type tumor, salivary gland poorly differentiated carcinoma, salivary gland squamous cell carcinoma, low-grade salivary gland mucoepidermoid carcinoma, and salivary gland acinic cell tumor

Sponsors

Other
University of Chicago
NIH
National Cancer Institute (NCI)

Inclusion Criteria

Exclusion Criteria

Detailed Description

RATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well dasatinib works in treating patients with recurrent or metastatic malignant salivary gland tumors.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00859937

Locations

  • London Regional Cancer Program at London Health Sciences Centre
    London, Ontario Canada
    (Recruiting)

    Contact info

    Eric Winquist, MD
    519-685-8500 ext. 58640
  • Princess Margaret Hospital
    Toronto, Ontario Canada
    (Recruiting)

    Contact info

    Lillian L. Siu, MD, FRCPC
    416-946-2911
  • CHUM - Hotel Dieu Hospital
    Montreal, Quebec Canada
    (Recruiting)

    Contact info

    Denis Soulieres, MD, MSC
    514-890-8200 ext. 27066
  • H. Lee Moffitt Cancer Center and Research Institute at University of South Florida
    Tampa, Florida United States
    (Recruiting)

    Contact info

    Clinical Trials Office - H. Lee Moffitt Cancer Center and Rese
    800-456-7121
  • Winship Cancer Institute of Emory University
    Atlanta, Georgia United States
    (Recruiting)

    Contact info

    Nabil Saba, MD
    404-686-3496
  • University of Chicago Cancer Research Center
    Chicago, Illinois United States
    (Recruiting)

    Contact info

    Clinical Trials Office - University of Chicago Cancer Research
    773-834-7424

See 15 more locations

  • Decatur Memorial Hospital Cancer Care Institute
    Decatur, Illinois United States
    (Recruiting)

    Contact info

    Clinical Trials Office - Decatur Memorial Hospital Cancer Care
    217-876-4750
  • Evanston Hospital
    Evanston, Illinois United States
    (Recruiting)

    Contact info

    Clinical Trials Office - Evanston Hospital
    847-570-1381
  • Ingalls Cancer Care Center at Ingalls Memorial Hospital
    Harvey, Illinois United States
    (Recruiting)

    Contact info

    Clinical Trials Office - Ingalls Cancer Care Center at Ingalls
    708-915-4673
  • Joliet Oncology-Hematology Associates, Limited - West
    Joliet, Illinois United States
    (Recruiting)

    Contact info

    Sanjiv S. Modi, MD
    815-730-3098
  • Cardinal Bernardin Cancer Center at Loyola University Medical Center
    Maywood, Illinois United States
    (Recruiting)

    Contact info

    Clinical Trials Office - Cardinal Bernardin Cancer Center
    708-226-4357
  • Oncology Hematology Associates of Central Illinois, PC - Peoria
    Peoria, Illinois United States
    (Recruiting)

    Contact info

    Sachdev P. Thomas, MD
    309-243-1000
  • Central Illinois Hematology Oncology Center
    Springfield, Illinois United States
    (Recruiting)

    Contact info

    Edem S. Agamah, MD, MS
    217-525-2500
  • Fort Wayne Medical Oncology and Hematology
    Fort Wayne, Indiana United States
    (Recruiting)

    Contact info

    Sreenivasa R. Nattam, MD
    260-484-8830
  • CCOP - Northern Indiana CR Consortium
    South Bend, Indiana United States
    (Recruiting)

    Contact info

    David A. Taber, MD
    574-647-3353
  • Greenebaum Cancer Center at University of Maryland Medical Center
    Baltimore, Maryland United States
    (Recruiting)

    Contact info

    Clinical Trials Office - Greenebaum Cancer Center at Universit
    800-888-8823
  • University of Michigan Comprehensive Cancer Center
    Ann Arbor, Michigan United States
    (Recruiting)

    Contact info

    Clinical Trials Office - University of Michigan Comprehensive
    800-865-1125
  • Oncology Care Associates, PLLC
    Saint Joseph, Michigan United States
    (Recruiting)

    Contact info

    Eric P. Lester, MD
    269-985-0029
  • David C. Pratt Cancer Center at St. John's Mercy
    Saint Louis, Missouri United States
    (Recruiting)

    Contact info

    Clinical Trials Office - David C. Pratt Cancer Center at St. J
    314-251-6770
  • Vanderbilt-Ingram Cancer Center
    Nashville, Tennessee United States
    (Recruiting)

    Contact info

    Jill Gilbert, MD
    Not Available
  • Virginia Commonwealth University Massey Cancer Center
    Richmond, Virginia United States
    (Recruiting)

    Contact info

    Clinical Trials Office -Virginia Commonwealth University Masse
    804-628-1939