Eligibility

Ages Eligible for Study

Up to 6 months

Genders Eligible for Study

Both

Keywords

Necrotizing Enterocolitis, Intragastric microdialysis, Peritoneal microdialysis, and Infants

Sponsors

Other

Odense University Hospital

Inclusion Criteria

- Neonates who are hospitalized because of suspicion of NEC.

- Neonates who has surgery because of NEC.

Exclusion Criteria

- Non-acceptance from the child's parents or custody holder

Detailed Description

NEC is a serious inflammatory bowel disease, which almost only strikes infants with low birth weight and low gestational age. The morbidity and mortality rates are high, and early diagnosis and treatment is mandatory. The primary aim of the present study is to investigate the clinical use of intragastric microdialysis and whether it is able to select patients, who may benefit from either medical or surgical therapy. The aim of intraperitoneal microdialysis is to evaluate whether changes in intraperitoneal microdialysis reflect the clinical outcome after laparotomy.