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A fasciculation (or "muscle twitch") is a small, local, involuntary muscle contraction (twitching) visible under the skin arising from the spontaneous discharge of a bundle of skeletal muscle fibres. In ALS fasciculations can occur in any muscle, including the tongue.
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| Reason | # Patients | Percentage of patients | |
|---|---|---|---|
| Baclofen | 17 | 100% | |
| Clonazepam | 11 | 65% | |
| Magnesium | 6 | 35% | |
| Diazepam | 5 | 29% | |
| Quinine Sulfate | 4 | 24% | |
| Acupuncture | 3 | 18% | |
| Gabapentin | 3 | 18% | |
| Riluzole | 2 | 12% | |
| Water water and more water | 2 | 12% | |
| AFO (ankle-foot orthosis) | 1 | 6% | |
| Augmentative Speech Device | 1 | 6% | |
| Avoid/Reduce Caffeine | 1 | 6% | |
| Beta Carotene | 1 | 6% | |
| Bi-PAP Humidifier | 1 | 6% | |
| Calcium | 1 | 6% | |
| Calcium Magnesium | 1 | 6% | |
| Clorazepate | 1 | 6% | |
| CoQ10 | 1 | 6% | |
| Creatine | 1 | 6% | |
| Epanutin caps | 1 | 6% | |
| Evening Primrose Oil | 1 | 6% | |
| Ibuprofen | 1 | 6% | |
| Nutritional supplements | 1 | 6% | |
| Occupational therapy | 1 | 6% | |
| Omega Fatty Acids | 1 | 6% | |
| Pneumonia vaccine | 1 | 6% | |
| Potassium | 1 | 6% | |
| Pramipexole | 1 | 6% | |
| Pregabalin | 1 | 6% | |
| Ropinirole | 1 | 6% | |
| Speech & Language Therapy | 1 | 6% | |
| Tissue Salt - Mag phos | 1 | 6% | |
| Tizanidine | 1 | 6% | |
| Trehalose | 1 | 6% | |
| Vitamin E | 1 | 6% |