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What is Zonisamide?

Zonisamide is an anticonvulsant drug that is used in combination with other medications to treat partial seizures in children over 16 years of age and adults with epilepsy. Off label it is used for Bipolar disorder.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Epilepsy 229 71 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Seizures (complex partial) 20 9 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none
Migraine headaches 14 2 Efficacy_moderate Efficacy_none
Seizures 8 0
Other 7 1 Efficacy_moderate
Headaches 7 2 Efficacy_moderate Efficacy_cant_tell

See all 289 patients currently taking Zonisamide

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Reported Side Effects

Side effects as an overall problem

Severe
 15
Moderate
 21
Mild
 23
None
 34

Commonly reported side effects, conditions, and hospitalizations associated with Zonisamide

Memory problems 5
Dizziness 3
Fatigue 3
Irritability 3
Weight loss 3
Constipation 2
See all 64 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Zonisamide. See all 20 dosages ►

  25 mg daily 50 mg daily 100 mg daily 150 mg daily 200 mg daily 300 mg daily 400 mg daily 500 mg daily 600 mg daily 700 mg daily
  6 Number of Patients: 6 13 Number of Patients: 13 37 Number of Patients: 37 9 Number of Patients: 9 65 Number of Patients: 65 54 Number of Patients: 54 50 Number of Patients: 50 31 Number of Patients: 31 23 Number of Patients: 23 6 Number of Patients: 6  

Reported Stop Reasons

Why Patients Stopped Taking Zonisamide (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 32   Side effects too severe: 43%
Did not seem to work 29   Did not seem to work: 39%
Doctor's advice 22   Doctor's advice: 30%
Other 7   Other: 9%
Expense 4   Expense: 5%
Course of treatment ended 4   Course of treatment ended: 5%
Personal research 3   Personal research: 4%
Change in health plan coverage 3   Change in health plan coverage: 4%
Not indicated 2   Not indicated: 3%

See all 72 patients who’ve stopped taking Zonisamide

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Zonisamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Zonisamide

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Zonisamide

Always
 79 85%
Usually
 12 13%
Sometimes
 1 1%
Never
 1 1%

Burden

Difficulty being on treatment

Burden of Zonisamide

Very
 5 5%
Somewhat
 4 4%
A little
 16 17%
Not at all
 68 73%

Cost

Paid out of pocket

Cost of Zonisamide

$200+
 3 5%
$100-199
 0 0%
$50-99
 5 9%
$25-49
 11 20%
< $25
 35 64%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 25, 2012.