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What is Dantrolene?

Dantrolene is a muscle relaxant used to treat spasticity associated with upper motor neuron disorders; to prevent and treat malignant hyperthermia. Off label it is used for neuroleptic malignant syndrome, a life-threatening disorder most often caused by an adverse reaction to certain drugs.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Stiffness/Spasticity 18 2 Efficacy_slight
Muscle tension 3 1 Efficacy_moderate
Muscle spasms 1 1 Efficacy_moderate
Nystagmus 1 0
Other 1 2 Efficacy_moderate
Cerebral Palsy 1 0

See all 20 patients currently taking Dantrolene

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 3
Mild
 2
None
 2

Commonly reported side effects, conditions, and hospitalizations associated with Dantrolene

Seizures 2
Constipation 1
Tiredness 1

Reported Dosages

  25 mg daily 50 mg daily 75 mg daily 100 mg daily 150 mg daily
  5 Number of Patients: 5 8 Number of Patients: 8 6 Number of Patients: 6 1 Number of Patients: 1 1 Number of Patients: 1  

Reported Stop Reasons

Why Patients Stopped Taking Dantrolene (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 3   Did not seem to work: 43%
Doctor's advice 2   Doctor's advice: 29%
Side effects too severe 2   Side effects too severe: 29%
Expense 1   Expense: 14%
Other 1   Other: 14%

See all 7 patients who’ve stopped taking Dantrolene

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Dantrolene

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Stopped Taking Dantrolene

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Dantrolene

Always
 5 71%
Usually
 0 0%
Sometimes
 1 14%
Never
 1 14%

Burden

Difficulty being on treatment

Burden of Dantrolene

Very
 0 0%
Somewhat
 1 14%
A little
 3 43%
Not at all
 3 43%

Cost

Paid out of pocket

Cost of Dantrolene

$200+
 0 0%
$100-199
 0 0%
$50-99
 1 25%
$25-49
 0 0%
< $25
 3 75%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 25, 2012.