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What is Trihexyphenidyl?

Trihexyphenidyl is anti-Parkinson's and anticholinergic agent used as adjunctive treatment of Parkinson's disease and for the treatment of drug-induced extrapyramidal symptoms.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Parkinson's Disease 56 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Tremor in hands 19 8 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Tremor 9 2 Efficacy_moderate
Other 6 1 Efficacy_moderate
Dystonia 3 2 Efficacy_moderate Efficacy_none
Increase effect of another treatment 2 2 Efficacy_moderate Efficacy_cant_tell

See all 93 patients currently taking Trihexyphenidyl

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Reported Side Effects

Side effects as an overall problem

Severe
 6
Moderate
 11
Mild
 9
None
 9

Commonly reported side effects, conditions, and hospitalizations associated with Trihexyphenidyl

Cognitive Confusion 9
Word fishing 6
Sleep problems 4
Dry mouth (xerostomia) 3
Sleepiness 3
Short temper 2
See all 21 reported side effects ▼ See top 6 reported side effects ▲

Reported Dosages

Frequently reported dosages based on patients currently taking Trihexyphenidyl. See all 23 dosages ►

  2mg as needed 1 mg daily 2 mg daily 2 mg/5 mL daily 3 mg daily 4 mg daily 2 x 2 mg/5 mL daily 5 mg daily 6 mg daily 15 mg daily
  3 Number of Patients: 3 4 Number of Patients: 4 21 Number of Patients: 21 4 Number of Patients: 4 6 Number of Patients: 6 15 Number of Patients: 15 3 Number of Patients: 3 3 Number of Patients: 3 17 Number of Patients: 17 4 Number of Patients: 4  

Reported Stop Reasons

Why Patients Stopped Taking Trihexyphenidyl (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 16   Side effects too severe: 44%
Doctor's advice 14   Doctor's advice: 39%
Did not seem to work 11   Did not seem to work: 31%
Other 4   Other: 11%
Personal research 2   Personal research: 6%
Expense 1   Expense: 3%

See all 35 patients who’ve stopped taking Trihexyphenidyl

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Trihexyphenidyl

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Stopped Taking Trihexyphenidyl

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Trihexyphenidyl

Always
 21 60%
Usually
 12 34%
Sometimes
 1 3%
Never
 1 3%

Burden

Difficulty being on treatment

Burden of Trihexyphenidyl

Very
 2 6%
Somewhat
 2 6%
A little
 9 26%
Not at all
 22 63%

Cost

Paid out of pocket

Cost of Trihexyphenidyl

$200+
 0 0%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 1 4%
< $25
 23 96%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 10, 2012.