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Brand Names: Agitane, Artane, Benzhexol, Broflex

What is Trihexyphenidyl? Trihexyphenidyl is an antimuscarinic drug used in the treatment of Parkinson's disease.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

56 patients in the community are taking or have taken Trihexyphenidyl.

Reason # Patients Percentage of patients
Treat Parkinson's 26 46%
Other 7 12%
Hand tremor 7 12%
disease-related symptoms 3 5%
General health 2 3%
dystonia 1 1%
Dry mouth (xerostomia) 1 1%
Slowness 1 1%
Excess saliva 1 1%
Pain, leg 1 1%
Stiffness/spasticity 1 1%
Support another treatment 1 1%

Dosages

Based on the patients currently taking Trihexyphenidyl.

Top 10 (Show all)

All (Show Top 10)

  0 mg day 0 mg none 1 mg day 1.5 mg day 2 mg day 3 mg day 4 mg day 5 mg day 6 mg day 8 mg day 10 mg day 12 mg day
  2 Number of Patients: 2 1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 15 Number of Patients: 15 1 Number of Patients: 1 6 Number of Patients: 6 1 Number of Patients: 1 8 Number of Patients: 8 2 Number of Patients: 2 3 Number of Patients: 3 1 Number of Patients: 1  

Duration

How long current patients have been taking Trihexyphenidyl or how long patients were taking Trihexyphenidyl before stopping.

Currently taking Trihexyphenidyl

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
5
6
3
3
12

Stopped taking Trihexyphenidyl

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
4
2
2
2
3
Why Patients Stopped Taking Trihexyphenidyl (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 8 53% Side effects too severe: 53%
Did not seem to work 6 40% Did not seem to work: 40%
Doctor's advice 4 27% Doctor's advice: 27%
Other 2 13% Other: 13%

Patient Reported Evaluations

Results from 10 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 25% 1
Moderate 50% 2
Slight 25% 1

Treat Parkinson's

Side-effects (as an overall problem)

Severe 20% 2
Moderate 20% 2
Mild 40% 4
None 20% 2

Top reported side-effects include: Cognitive confusion, Sleep problems, Word fishing

Summary results are based on 10 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 10)

  • PD Walker
    Mouth/throat: mild
    Arms: mild
    Chest: mild
    Legs: mild
    See profile
  • PD Walker
  • by PD Walker
    Sep 19, 2008
  • EfficacyMajor
  • Side-effectsModerate
  • Hand tremor

  • GoCats76
    Mouth/throat: mild
    Arms: none
    Chest: mild
    Legs: mild
    See profile
  • GoCats76
  • by GoCats76
    Nov 16, 2008
  • EfficacyModerate
  • Side-effectsModerate
  • dystonia

See all evaluation results for Trihexyphenidyl



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