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Brand Names: Comtan, Comtess

What is Entacapone? Entacapone is a catechol-o-methyltransferase (COMT) inhibitor drug which enhances the transport of levodopa to the brain, improving the efficacy of levodopa containing drugs such as Sinemet.

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

113 patients in the community are taking or have taken Entacapone.

Reason # Patients Percentage of patients
Treat Parkinson's 81 71%
Other 7 6%
Stiffness/spasticity 6 5%
Support another treatment 4 3%
disease-related symptoms 1 <1%
Slowness 1 <1%

Dosages

Based on the patients currently taking Entacapone.

Top 10 (Show all)

All (Show Top 10)

  0 mg day 1 mg day 20 mg day 200 mg none 200 mg day 300 mg day 400 mg day 600 mg day 800 mg day 1000 mg day 1200 mg day 1400 mg day
  8 Number of Patients: 8 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 13 Number of Patients: 13 4 Number of Patients: 4 9 Number of Patients: 9 23 Number of Patients: 23 24 Number of Patients: 24 9 Number of Patients: 9 3 Number of Patients: 3 1 Number of Patients: 1  

Duration

How long current patients have been taking Entacapone or how long patients were taking Entacapone before stopping.

Currently taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
4
6
8
12
12
23

Stopped taking Entacapone

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
2
2
2
4
2
3
Why Patients Stopped Taking Entacapone (multiple reasons could be selected)
Reason # Patients Percentage of patients
Side effects too severe 7 44% Side effects too severe: 44%
Other 6 38% Other: 38%
Did not seem to work 5 31% Did not seem to work: 31%
Doctor's advice 4 25% Doctor's advice: 25%
Course of treatment ended 1 6% Course of treatment ended: 6%

Patient Reported Evaluations

Results from 7 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Major 20% 1
Moderate 40% 2
Slight 20% 1
Can't tell 20% 1

Treat Parkinson's

Side-effects (as an overall problem)

Severe 0% 0
Moderate 0% 0
Mild 29% 2
None 71% 5

Top reported side-effects include: Increased dyskenisia

Summary results are based on 7 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 7)

  • asb
    Mouth/throat: none
    Arms: mild
    Chest: none
    Legs: mild
    See profile
  • asb
  • by asb
    Sep 14, 2008
  • EfficacyModerate
  • Side-effectsNone
  • Treat Parkinson's
Advice/Tips
Almost immediate improvement against insomnia, but gradual backslide over 2 months. Follow up has been Sinemet CR

  • btrflynana2
    Autonomic: Moderate
    Mood: Very bad
    Cognition: Moderate
    Head: mild
    Arms: none
    Legs: mild
    Tremors: none
    See profile
  • btrflynana2
  • by btrflynana2
    Nov 23, 2008
  • EfficacyMajor
  • Side-effectsNone
  • Other

See all evaluation results for Entacapone



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