PatientsLikeMe : Carbidopa-Entacapone-Levodopa Treatment Report

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What is Carbidopa-Entacapone-Levodopa?

The combination of levodopa, carbidopa, and entacapone is used for Parkinson's Disease. Levodopa is the precursor to dopamine, carbidopa slows the breakdown of levodopa, while entacapone improves the efficacy of levodopa.

Reasons taken & Efficacy

Reasons and Efficacy
Reasons taken	# of patients	# of patients evaluated by
Treat Parkinson's	223	51
Stiffness/Spasticity	12	2
Other	12	4
Support another treatment	7	2
Mobility	4	0
Parkinson's Disease	4	1
Treat Parkinson's Disease	3	1
disease-related symptoms	2	0
on/off	2	2
Stiffness	2	0
Slowness	2	0
Parkinsonism	2	0
bad reaction	1	0
Treat my PSP	1	0
Tremors, hands	1	1
balance became worse	1	0
Slurred speech	1	0
Tremors	1	0
Assistive communication	1	0
TWITCHING & JUMPING OF LEGS	1	0
Brain fog	1	0
General health	1	0
Hand tremor	1	0
level out dyskinesia	1	0
Memory problems	1	0
Don't know	1	0
foot dystonia	1	0

See all 27 reasons taken ▼

See all 300 patients currently taking Carbidopa-Entacapone-Levodopa

Mouse over the table for more information

Side Effects

Side effects as an overall problem

Severe	7	12%
Moderate	15	25%
Mild	17	29%
None	20	34%

Most commonly reported side effects

Dyskinesia	11	19%
legs cramping when wearing off	8	14%
tremors increase when wearing off	8	14%
Nausea	7	12%
Fatigue	5	8%
Urine amber color	5	8%
Weight gain	4	7%
bladder retention	4	7%
Cognitive confusion	3	5%
vision distortion	3	5%
Emotional cycling	3	5%
Insomnia	3	5%
hyperkinsesia	2	3%
involentary movements	2	3%
Diarrhea	1	2%
involuntary movment	1	2%
High blood pressure (Hypertension)	1	2%
darker urination(stains underwear)	1	2%
Depression with suicidal thoughts	1	2%
chest tightness-breathing difficulty	1	2%
Confusion	1	2%
WIRED	1	2%
Vomiting	1	2%
Stomach pain	1	2%

Mild
Moderate
Severe

See all 24 reported side effects ▼

Dosages

Top 10 dosages based on patients currently taking Carbidopa-Entacapone-Levodopa. See all 61 dosages ►

100 mg all the time (24/7)	100mg as needed	25 mg-200 mg-100 mg all the time (24/7)	25 mg-200 mg-100 mg daily	daily	0.05 mg daily	3 mg daily	4 mg daily	4 other daily	5 intl units daily	5 mg daily	6 mg daily	6 other daily	25 mg daily	12.5 mg-200 mg-50 mg daily	50 mg daily	75 mg daily	80 mg daily	100 mg daily	25 mg-200 mg-100 mg daily	2 x 12.5 mg-200 mg-50 mg daily	125 mg daily	150 mg daily	150 other daily	37.5 mg-200 mg-150 mg daily	3 x 12.5 mg-200 mg-50 mg daily	200 mg daily	200 other daily	2 x 25 mg-200 mg-100 mg daily	4 x 12.5 mg-200 mg-50 mg daily	3 x 18.75 mg-200 mg-75 mg daily	250 mg daily	5 x 12.5 mg-200 mg-50 mg daily	2 x 37.5 mg-200 mg-150 mg daily	300 mg daily	3 x 25 mg-200 mg-100 mg daily	6 x 12.5 mg-200 mg-50 mg daily	350 mg daily	400 mg daily	4 x 25 mg-200 mg-100 mg daily	8 x 12.5 mg-200 mg-50 mg daily	3 x 37.5 mg-200 mg-150 mg daily	450 mg daily	4 x 31.25 mg-200 mg-125 mg daily	500 mg daily	5 x 25 mg-200 mg-100 mg daily	3 x 50 mg-200 mg-200 mg daily	4 x 37.5 mg-200 mg-150 mg daily	600 mg daily	6 x 25 mg-200 mg-100 mg daily	625 mg daily	650 mg daily	700 mg daily	7 x 25 mg-200 mg-100 mg daily	5 x 37.5 mg-200 mg-150 mg daily	750 mg daily	800 mg daily	8 x 25 mg-200 mg-100 mg daily	6 x 37.5 mg-200 mg-150 mg daily	900 mg daily	1200 mg daily
1	1	1	1	12	1	1	5	1	1	1	1	1	1	3	4	3	1	13	14	5	1	8	1	6	6	12	2	3	9	1	1	4	1	22	27	2	1	13	23	1	12	7	2	4	12	2	13	12	5	1	1	2	1	6	3	3	2	5	4	1

Stop Reasons

Why Patients Stopped Taking Carbidopa-Entacapone-Levodopa (multiple reasons could be selected)
Reason	# Patients	Percentage of patients
Side effects too severe	26	39%
Doctor's advice	15	23%
Did not seem to work	14	21%
Expense	12	18%
Other	7	11%
Not indicated	5	8%
Personal research	1	2%

See all 64 patients who’ve stopped taking Carbidopa-Entacapone-Levodopa

Duration See details about how long patients take this treatment ▼

Currently Taking Carbidopa-Entacapone-Levodopa

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
2	9	13	33	33	68

Stopped Taking Carbidopa-Entacapone-Levodopa

0-1 month	1-3 months	3-6 months	6 months-1year	1-2 years	2 years or more
6	13	10	16	10	11

Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Always	44	75%
Usually	13	22%
Sometimes	2	3%
Never	0	0%

Burden

Difficulty being on treatment

Very	7	12%
Somewhat	6	10%
A little	18	31%
Not at all	28	47%

Cost

Paid out of pocket

$200+	2	3%
$100-199	5	8%
$50-99	7	12%
$25-49	8	14%
< $25	19	32%

See more information, including instructions, precautions, side effects, and interactions.

Patient Evaluations

See all 59 patient evaluations

rose5

Sex: F

Mouth/throat: mild

Arms: moderate

Chest: mild

Legs: mild

See profile
rose5

4 x 25 mg-200 mg-100 mg daily

since Oct 28, 2009
Efficacy Major for Treat Parkinson's
Side Effects None
See full evaluation

mbsxxx

Sex: M

Mouth/throat: mild

Arms: mild

Chest: mild

Legs: mild

See profile
mbsxxx

6 x 12.5 mg-200 mg-50 mg daily

since Sep 16, 2008
Efficacy Moderate for Treat Parkinson's
Side Effects Mild
See full evaluation

server

Sex: M

Mouth/throat: none

Arms: none

Chest: none

Legs: none

See profile
server

300 mg daily

since Oct 04, 2008
Efficacy Major for Treat Parkinson's
Side Effects None
Advice/Tips take this on the right time, divide the moments that you take this meds to regular times, mine are 8am 1pm and 6pm (time frame 5 hrs). See full evaluation

See all 59 patient evaluations

Forum

See 18 topics tagged with Stalevo

There are 388 posts in our forum about Carbidopa-Entacapone-Levodopa. Join now and see what people are saying.

Report created on November 21, 2009.

100 mg all the time (24/7)	100mg as needed	25 mg-200 mg-100 mg all the time (24/7)	25 mg-200 mg-100 mg daily	daily	0.05 mg daily	3 mg daily	4 mg daily	4 other daily	5 intl units daily	5 mg daily	6 mg daily	6 other daily	25 mg daily	12.5 mg-200 mg-50 mg daily	50 mg daily	75 mg daily	80 mg daily	100 mg daily	25 mg-200 mg-100 mg daily	2 x 12.5 mg-200 mg-50 mg daily	125 mg daily	150 mg daily	150 other daily	37.5 mg-200 mg-150 mg daily	3 x 12.5 mg-200 mg-50 mg daily	200 mg daily	200 other daily	2 x 25 mg-200 mg-100 mg daily	4 x 12.5 mg-200 mg-50 mg daily	3 x 18.75 mg-200 mg-75 mg daily	250 mg daily	5 x 12.5 mg-200 mg-50 mg daily	2 x 37.5 mg-200 mg-150 mg daily	300 mg daily	3 x 25 mg-200 mg-100 mg daily	6 x 12.5 mg-200 mg-50 mg daily	350 mg daily	400 mg daily	4 x 25 mg-200 mg-100 mg daily	8 x 12.5 mg-200 mg-50 mg daily	3 x 37.5 mg-200 mg-150 mg daily	450 mg daily	4 x 31.25 mg-200 mg-125 mg daily	500 mg daily	5 x 25 mg-200 mg-100 mg daily	3 x 50 mg-200 mg-200 mg daily	4 x 37.5 mg-200 mg-150 mg daily	600 mg daily	6 x 25 mg-200 mg-100 mg daily	625 mg daily	650 mg daily	700 mg daily	7 x 25 mg-200 mg-100 mg daily	5 x 37.5 mg-200 mg-150 mg daily	750 mg daily	800 mg daily	8 x 25 mg-200 mg-100 mg daily	6 x 37.5 mg-200 mg-150 mg daily	900 mg daily	1200 mg daily
1	1	1	1	12	1	1	5	1	1	1	1	1	1	3	4	3	1	13	14	5	1	8	1	6	6	12	2	3	9	1	1	4	1	22	27	2	1	13	23	1	12	7	2	4	12	2	13	12	5	1	1	2	1	6	3	3	2	5	4	1

100 mg all the time (24/7)	100mg as needed	25 mg-200 mg-100 mg all the time (24/7)	25 mg-200 mg-100 mg daily	daily	0.05 mg daily	3 mg daily	4 mg daily	4 other daily	5 intl units daily	5 mg daily	6 mg daily	6 other daily	25 mg daily	12.5 mg-200 mg-50 mg daily	50 mg daily	75 mg daily	80 mg daily	100 mg daily	25 mg-200 mg-100 mg daily	2 x 12.5 mg-200 mg-50 mg daily	125 mg daily	150 mg daily	150 other daily	37.5 mg-200 mg-150 mg daily	3 x 12.5 mg-200 mg-50 mg daily	200 mg daily	200 other daily	2 x 25 mg-200 mg-100 mg daily	4 x 12.5 mg-200 mg-50 mg daily	3 x 18.75 mg-200 mg-75 mg daily	250 mg daily	5 x 12.5 mg-200 mg-50 mg daily	2 x 37.5 mg-200 mg-150 mg daily	300 mg daily	3 x 25 mg-200 mg-100 mg daily	6 x 12.5 mg-200 mg-50 mg daily	350 mg daily	400 mg daily	4 x 25 mg-200 mg-100 mg daily	8 x 12.5 mg-200 mg-50 mg daily	3 x 37.5 mg-200 mg-150 mg daily	450 mg daily	4 x 31.25 mg-200 mg-125 mg daily	500 mg daily	5 x 25 mg-200 mg-100 mg daily	3 x 50 mg-200 mg-200 mg daily	4 x 37.5 mg-200 mg-150 mg daily	600 mg daily	6 x 25 mg-200 mg-100 mg daily	625 mg daily	650 mg daily	700 mg daily	7 x 25 mg-200 mg-100 mg daily	5 x 37.5 mg-200 mg-150 mg daily	750 mg daily	800 mg daily	8 x 25 mg-200 mg-100 mg daily	6 x 37.5 mg-200 mg-150 mg daily	900 mg daily	1200 mg daily
1	1	1	1	12	1	1	5	1	1	1	1	1	1	3	4	3	1	13	14	5	1	8	1	6	6	12	2	3	9	1	1	4	1	22	27	2	1	13	23	1	12	7	2	4	12	2	13	12	5	1	1	2	1	6	3	3	2	5	4	1

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Carbidopa-Entacapone-Levodopa Treatment Report