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Divalproex sodium Treatment Report
Most Popular Brands: Depakote, Depakote ER, Novo-Divalproex (Show all)
Most Popular Brands: Depakote, Depakote ER, Novo-Divalproex, Epival, Valtas OD (Show top 3)
Generic Name: Divalproex sodium
See also: Valproate Sodium, Valproic Acid
What is Divalproex sodium?
Divalproex sodium is chemically compounded from sodium valproate and valproic acid in a 1:1 ratio. It is a delayed release, enteric coated tablet used for seizures, mania associated with bipolar disorder and prevention of migranes.
Reasons taken & Efficacy
| Reasons taken |
# of patients
Efficacy
|
Major | Moderate | Slight | None | Can’t tell | # of patients evaluated by |
|---|---|---|---|---|---|---|---|
| Treat my mood condition(s) | 108 |
|
|
|
|
|
37 |
| Bipolar Disorder | 57 |
|
|
|
|
19 | |
| Seizures | 45 |
|
|
|
|
17 | |
| Other | 35 |
|
|
|
|
8 | |
| Bipolar manic episodes | 13 |
|
|
|
5 | ||
| Migraine | 11 | 0 | |||||
| Migraine Headaches | 11 |
|
|
3 | |||
| Headaches | 11 |
|
1 | ||||
| Anxiety | 8 |
|
2 | ||||
| Depression | 8 | 0 | |||||
| Support another treatment | 6 |
|
1 | ||||
| Epilepsy | 6 |
|
1 | ||||
| Mood swings | 5 |
|
|
2 | |||
| Emotional lability | 3 | 0 | |||||
| Pain | 3 | 0 | |||||
| Mania | 2 | 0 | |||||
| complex partial seizure | 2 | 0 | |||||
| mood stabalizer | 1 | 0 | |||||
| Depression with anxiety | 1 | 0 | |||||
| Parkinson's Disease PD | 1 | 0 | |||||
| Nerve pain | 1 |
|
1 | ||||
| Problems concentrating | 1 | 0 | |||||
| Seizures (grand mal/tonic-clonic) | 1 |
|
1 | ||||
| Major Depressive Disorder | 1 |
|
2 | ||||
| Muscle spasms | 1 |
|
1 | ||||
| Multiple Sclerosis MS | 1 | 0 | |||||
| Sleepiness | 1 | 0 | |||||
| Bipolar rapid cycling | 1 |
|
1 | ||||
| General health | 1 |
|
|
2 | |||
| Trigeminal neuralgia | 1 | 0 | |||||
| complex partial | 1 |
|
1 | ||||
| Don't know | 1 | 0 | |||||
| seizures and migraines | 1 |
|
1 | ||||
| Tics | 1 |
|
1 | ||||
| Impulsive behaviors | 1 |
|
1 | ||||
| Deadened emotions | 1 | 0 | |||||
| Insomnia | 1 |
|
1 |
See all 305 patients currently taking Divalproex sodium
Mouse over the table for more information
Side Effects
Most commonly reported side effects
|
Weight gain
|
34 | 49% |
11
20
16
|
|---|---|---|---|
|
Fatigue
|
20 | 29% |
6
7
7
|
|
Drowsiness
|
12 | 17% |
6
4
3
|
|
Grogginess
|
11 | 16% |
4
4
4
|
|
Nausea
|
9 | 13% |
5
3
2
|
|
Tremor
|
9 | 13% |
2
3
4
|
|
Slowed thinking
|
8 | 12% |
3
4
2
|
|
Hair loss (alopecia)
|
6 | 9% |
1
4
1
|
|
thirst
|
6 | 9% |
2
2
2
|
|
Hair thinning
|
5 | 7% |
4
3
1
|
|
Diarrhea
|
5 | 7% |
3
1
1
|
|
Hair loss
|
4 | 6% |
2
1
1
|
|
Abnormal thoughts
|
3 | 4% |
0
0
3
|
|
Abnormal dreams
|
3 | 4% |
0
1
2
|
|
Agitation/restlessness
|
3 | 4% |
2
1
0
|
|
Hair curling
|
2 | 3% |
1
1
1
|
|
Drowsiness,brain fog,slurred speech,sleepiness.
|
1 | 1% |
0
0
0
|
|
Dizziness with nausea
|
1 | 1% |
0
0
1
|
|
lazyness
|
1 | 1% |
1
1
1
|
|
Balance, Brain Fog, Fatigue, Depression,Lower Back, Memory , Muscle & Joint Pain, Muscle Spasm, Insomnia
|
1 | 1% |
0
1
0
|
|
Nausea and vomiting
|
1 | 1% |
1
0
0
|
|
Irritability
|
1 | 1% |
0
1
0
|
|
Elevated liver enzymes
|
1 | 1% |
0
0
1
|
|
Vomiting
|
1 | 1% |
0
1
0
|
|
depressed facial expression
|
1 | 1% |
0
1
0
|
|
Muscle pain
|
1 | 1% |
0
1
0
|
|
Brain fog
|
1 | 1% |
1
0
0
|
|
Daytime sleepiness
|
1 | 1% |
1
0
0
|
|
flat affect
|
1 | 1% |
0
1
0
|
|
Addiction
|
1 | 1% |
1
0
0
|
|
hiar loss
|
1 | 1% |
0
0
1
|
|
Excessive daytime sleepiness (somnolence)
|
1 | 1% |
0
0
1
|
|
Spinning dizziness (vertigo)
|
1 | 1% |
1
1
0
|
|
unpredictable menstrual cycle
|
1 | 1% |
0
0
1
|
|
Muscle twitching in right hand and leg
|
1 | 1% |
0
1
0
|
|
digestive problems, shaking, some brain zaps
|
1 | 1% |
0
1
0
|
|
Heavy sedation
|
1 | 1% |
0
1
0
|
|
Cramps in legs
|
1 | 1% |
0
1
0
|
|
Memory Issues (Brain Fog)
|
1 | 1% |
0
1
1
|
|
Worsening vision
|
1 | 1% |
0
1
0
|
|
Tiredness
|
1 | 1% |
1
0
0
|
|
dizzy, shaking, brain "zaps"
|
1 | 1% |
0
0
1
|
- Mild
- Moderate
- Severe
Dosages
Top 10 dosages based on patients currently taking Divalproex sodium. See all 30 dosages ►
All dosages based on patients currently taking Divalproex sodium. See top 10 dosages ◄
| 250 mg all the time (24/7) | 500 mg as needed | daily | 1 other daily | 2 g daily | 2 mg daily | 3 tbs. daily | 20 mg daily | 30 mg daily | 500 mg | 100 mg daily | 125 mg daily | 250 mg daily | 375 mg daily | 500 mg daily | 750 mg daily | 775 mcg daily | 775 mg daily | 875 mg daily | 900 mg daily | 1000 g daily | 1000 mg daily | 1125 mg daily | 1250 mg daily | 1500 mg daily | 1750 mg daily | 2000 mg daily | 2250 mg daily | 2500 mg daily | 3000 mg daily | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1
|
1
|
2
|
1
|
2
|
1
|
1
|
1
|
1
|
1
|
1
|
5
|
30
|
4
|
72
|
30
|
1
|
1
|
1
|
1
|
1
|
79
|
1
|
1
|
45
|
4
|
22
|
1
|
2
|
2
|
||
Stop Reasons
| Reason | # Patients | Percentage of patients | |
|---|---|---|---|
|
Side effects too severe
|
47 | 49% |
|
|
Did not seem to work
|
31 | 33% |
|
|
Other
|
26 | 27% |
|
|
Doctor's advice
|
22 | 23% |
|
|
Expense
|
9 | 9% |
|
|
Personal research
|
4 | 4% |
|
|
Course of treatment ended
|
3 | 3% |
|
|
Not indicated
|
2 | 2% |
|
Duration See details about how long patients take this treatment ▼ Duration Hide details ▲
Adherence, Burden & Cost See details from patient evaluations ▼ Adherence, Burden & Cost Hide details ▲
See more information, including instructions, precautions, side effects, and interactions.
Patient Evaluations
See all 95 patient evaluations
-
- pinkgirl82
- Sex: F
- Depression: 1
- Emotional: 1
- Compulsion: 1
- Anxiety: 1
- Mania: 2
- Physical: 2
- External Stress: Moderate
- 27 F
- Function: High
- Distress: Low
- See profile
-
- pinkgirl82
- 500 mg daily
- since Jan 08, 2009
-
Efficacy
Moderate
for Bipolar rapid cycling
-
Side Effects
Mild
- Advice/Tips I have only been taking this medicine just over a week and it seems to be working so far. I have experienced some very unpredictable nausea/vomitting. Its n... See full evaluation
-
- searchinglikeme
- Sex: F
- Depression: 0
- Emotional: 1
- Compulsion: 0
- Anxiety: 0
- Mania: 0
- Physical: 0
- External Stress: Low
- 41 F
- Function: High
- Distress: Low
- See profile
-
-
- searchinglikeme
- 750 mg daily
- since Mar 10, 2008
-
Efficacy
None
for Treat my mood condition(s)
-
Side Effects
Severe
- See full evaluation
-
- Fairy Goth Mother
- Sex: F
- Sensation: Moderate
- Overall: Mild
- Cognition: moderate
- Vision: moderate
- Speech: none
- Swallowing: none
- Upper limb: moderate
- Walking: mild
- See profile
-
-
- Fairy Goth Mother
- 500 mg daily
- since Sep 19, 2008
-
Efficacy
Major
for Other
-
Side Effects
None
- Advice/Tips Works great for migraines. See full evaluation
See all 95 patient evaluations
Report created on March 22, 2010.
© 2005-2010 PatientsLikeMe. Information on PatientsLikeMe.com does not constitute medical advice.
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