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Brand Names: Deplin, Metanx

What is L-methylfolate? L-methylfolate is the natural, active form of folate. Folate supplementation has potential to impact prenatal care, homocysteine management and the treatment of depression, dementia and cardiovascular conditions. Read more...Click to read more below

See more information, including instructions, precautions, side effects, and interactions.


Reasons Taken

18 patients in the community are taking or have taken L-methylfolate.

Reason # Patients Percentage of patients
Treat my mood condition(s) 11 61%
Other 2 11%
Cold feet 1 5%
General health 1 5%
Fatigue 1 5%
Slow my ALS progress 1 5%

Dosages

Based on the patients currently taking L-methylfolate.

  0 - day 0 mg day 1 mg day 1 tbs. day 2 mg day 2 day 7.5 mg day 15 mg day 500 mg day 2000 mg day
  1 Number of Patients: 1 2 Number of Patients: 2 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1 4 Number of Patients: 4 1 Number of Patients: 1 1 Number of Patients: 1 1 Number of Patients: 1  

Duration

How long current patients have been taking L-methylfolate or how long patients were taking L-methylfolate before stopping.

Currently taking L-methylfolate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
1
0
2
3
3
1

Stopped taking L-methylfolate

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
2
2
0
0
0
Why Patients Stopped Taking L-methylfolate (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 2 50% Did not seem to work: 50%
Expense 1 25% Expense: 25%
Other 1 25% Other: 25%

Patient Reported Evaluations

Results from 4 patient evaluations. See the overall results and all individual evaluations.

Efficacy (Effect based on reason taken)

Moderate 67% 2
Can't tell 33% 1

Treat my mood condition(s)

Side-effects (as an overall problem)

Severe 0% 0
Moderate 0% 0
Mild 0% 0
None 100% 4

Top reported side-effects include:

Summary results are based on 4 individual responses. For more information, see overall results for Adherence, Burden and Cost.

Individual Patient Reported Evaluations (2 of 4)

  • searchinglikeme
    Depression: 1
    Emotional: 1
    Compulsion: 0
    Anxiety: 0
    Mania: 0
    Physical: 0
    External Stress: Moderate
    39 F
    Function: High
    Distress: Low
    See profile
  • searchinglikeme
  • by searchinglikeme
    May 04, 2008
  • EfficacyCan't tell
  • Side-effectsNone
  • Treat my mood condition(s)

  • StabilityDream
    Depression: 2
    Emotional: 2
    Compulsion: 0
    Anxiety: 2
    Mania: 0
    Physical: 2
    External Stress: Severe
    42 F
    Function: Moderate
    Distress: Low
    See profile
  • by StabilityDream
    Sep 07, 2008
  • EfficacyModerate
  • Side-effectsNone
  • Treat my mood condition(s)
Advice/Tips
I was very excited about starting Deplin, because it made sense that my brain was just missing "something" because I didn't respond well to depression meds long-term. It was extremely disappointing for the first few months and my depression worsened. I do believe now, though, that it is helping. My psych. said it could be that I just had a major imbalance and it took longer for it to kick in. I'm doing MUCH better now. I'm staying on it, and I hope it continues to improve my condition(s).

See all evaluation results for L-methylfolate



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