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What is Ursodiol?

Ursodiol, also known as ursodeoxycholic acid (UDCA), is a bile acid, a substance naturally produced by the body and stored in the gall bladder. It is used to dissolve gallstones in patients who do not want surgery or cannot have surgery to remove gallstones. Read more...Click to read more below

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Primary biliary cirrhosis 21 3 Efficacy_moderate Efficacy_none
ALS (Amyotrophic Lateral Sclerosis) 10 7 Efficacy_slight Efficacy_none Efficacy_cant_tell
Other 10 0
Participate in clinical trial 5 2 Efficacy_moderate Efficacy_cant_tell
Liver disease 4 0
Gall stones 3 1 Efficacy_none

See all 70 patients currently taking Ursodiol

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Reported Side Effects

Side effects as an overall problem

Severe
2
Moderate
1
Mild
2
None
11

Commonly reported side effects, conditions, and hospitalizations associated with Ursodiol

Weight loss 1
Diarrhea 1
Diarrhea chronic 1
Low cholesterol 1

Reported Dosages

Frequently reported dosages based on patients currently taking Ursodiol. See all 15 dosages

  250 mg daily 500 mg daily 600 mg daily 750 mg daily 900 mg daily 1,000 mg daily 1,200 mg daily 1,500 mg daily 1,800 mg daily 3,000 mg daily
  2 Number of Patients: 2 5 Number of Patients: 5 16 Number of Patients: 16 5 Number of Patients: 5 16 Number of Patients: 16 11 Number of Patients: 11 2 Number of Patients: 2 4 Number of Patients: 4 2 Number of Patients: 2 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Ursodiol (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 5   Did not seem to work: 42%
Side effects too severe 3   Side effects too severe: 25%
Course of treatment ended 2   Course of treatment ended: 17%
Personal research 1   Personal research: 8%
Doctor's advice 1   Doctor's advice: 8%
Other 1   Other: 8%

See all 12 patients who’ve stopped taking Ursodiol

Currently Taking Ursodiol

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0

Stopped Taking Ursodiol

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Ursodiol

Always
13 81%
Usually
3 19%
Sometimes
0 0%
Never
0 0%

Burden

Difficulty being on treatment

Burden of Ursodiol

Very
1 6%
Somewhat
2 13%
A little
2 13%
Not at all
11 69%

Cost

Paid out of pocket

Cost of Ursodiol

$200+
0 0%
$100-199
1 9%
$50-99
0 0%
$25-49
0 0%
< $25
10 91%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.