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Brand Names:
Sirdalud Retard, Tizanidine HCl, Zanaflex
Generic Name: Tizanidine
What is Tizanidine? Tizanidine is a centrally acting alpha2-adrenergic agonist. It is a skeletal muscle relaxant used for treatment of muscle spasticity. Off label it is used for tension headaches, low back pain, and trigeminal neuralgia.
See more information, including instructions, precautions, side effects, and interactions.
473 patients in the community are taking or have taken Tizanidine.
| Reason | # Patients | Percentage of patients |
|---|---|---|
| Stiffness/spasticity | 302 | 63% |
| Other | 46 | 9% |
| Pain | 19 | 4% |
| disease-related symptoms | 14 | 2% |
| Muscle Spasms, feet and toes | 6 | 1% |
| Muscle spasms, neck and shoulders | 6 | 1% |
| Muscle spasms | 5 | 1% |
| Spasms | 4 | <1% |
| Insomnia | 3 | <1% |
| General health | 3 | <1% |
| Slow my MS progress | 3 | <1% |
| Fasciculations | 3 | <1% |
| Support another treatment | 2 | <1% |
| Calf, feet cramps and muscle spasms | 2 | <1% |
| Depression | 2 | <1% |
| Muscle tension | 2 | <1% |
| MS Hug, or girdle-band sensation, stomach/chest/thighs | 1 | <1% |
| Muscle twitching (fasciculations) | 1 | <1% |
| Pain, leg | 1 | <1% |
| Spasms, calves | 1 | <1% |
| Night-time leg spasms | 1 | <1% |
| Headaches/ Migraines | 1 | <1% |
| Burning sensation, soles of feet | 1 | <1% |
| Muscle spasms, lower back | 1 | <1% |
| Fatigue | 1 | <1% |
| Sexual dysfunction | 1 | <1% |
| Muscle cramping, spasms | 1 | <1% |
| Cramps, calf muscles | 1 | <1% |
| twitches and jerks | 1 | <1% |
| tonic spasm | 1 | <1% |
| Don't know | 1 | <1% |
| Mobility | 1 | <1% |
| Treat Parkinson's | 1 | <1% |
| Stiff neck | 1 | <1% |
| 0 mg Daily | 2 mg As needed | 4 mg As needed | 10 mg As needed | 16 mg All the time (24/7) | 16 mg As needed | 20 mg As needed | 1 mg Daily | 2 mg All the time (24/7) | 2 mg As needed | 2 mg Daily | 3 mg Daily | 3 Daily | 4 mg As needed | 4 mg Daily | 5 mg Daily | 6 mg Daily | 8 mg Daily | 10 mg Daily | 12 mg As needed | 12 mg Daily | 14 mg Daily | 16 mg Daily | 18 mg Daily | 20 mg Daily | 24 mg Daily | 28 mg Daily | 30 mg Daily | 32 mg Daily | 40 mg Daily | 50 mg Daily | 100 mg Daily | 300 mg Daily | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
40
|
9
|
12
|
1
|
1
|
1
|
1
|
1
|
1
|
2
|
32
|
2
|
1
|
5
|
105
|
6
|
20
|
55
|
8
|
1
|
30
|
2
|
26
|
6
|
11
|
16
|
1
|
4
|
4
|
1
|
1
|
2
|
2
|
||
How long current patients have been taking Tizanidine or how long patients were taking Tizanidine before stopping.
Results from 42 patient evaluations. See the overall results and all individual evaluations.
| Major | 38% | 11 |
|---|---|---|
| Moderate | 31% | 9 |
| Slight | 24% | 7 |
| None | 7% | 2 |
Stiffness/spasticity
| Severe | 10% | 4 |
|---|---|---|
| Moderate | 26% | 11 |
| Mild | 36% | 15 |
| None | 29% | 12 |
Top reported side-effects include: sleepy, Fatigue, makes me very sleepy
Summary results are based on 42 individual responses. For more information, see overall results for Adherence, Burden and Cost.