What is Baclofen?

An example of Baclofen

Baclofen is a skeletal muscle relaxant and anti-spastic agent used for the treatment of reversible spasticity associated with multiple sclerosis or spinal cord lesions.

Reported Purpose & Perceived Effectiveness

Reasons and Perceived effectiveness
Perceived Effectiveness
Purpose # of patients # of patients with evaluations
Major
Moderate
Slight
None
Can’t tell
1,923 443 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
1,680 212 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
703 222 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
293 43 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
166 43 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
90 21 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell

See all 3,687 patients currently taking Baclofen

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Reported Side Effects

Side effects as an overall problem

Severe
78
Moderate
144
Mild
252
None
431

Commonly reported side effects, conditions, and hospitalizations associated with Baclofen

103
95
63
48
36
34
See all 175 reported side effects See top 6 reported side effects

Reported Dosages

Frequently reported dosages based on patients currently taking Baclofen. See all 164 dosages

  10mg as needed daily 10 mg daily 20 mg daily 30 mg daily 40 mg daily 50 mg daily 60 mg daily 80 mg daily 120 mg daily
  172 Number of Patients: 172 77 Number of Patients: 77 544 Number of Patients: 544 578 Number of Patients: 578 606 Number of Patients: 606 369 Number of Patients: 369 96 Number of Patients: 96 456 Number of Patients: 456 284 Number of Patients: 284 75 Number of Patients: 75  

Reported Stop Reasons

Why Patients Stopped Taking Baclofen (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 309   Did not seem to work: 39%
Side effects too severe 248   Side effects too severe: 31%
Other 153   Other: 19%
Doctor's advice 94   Doctor's advice: 12%
Course of treatment ended 48   Course of treatment ended: 6%
Personal research 23   Personal research: 3%
Not indicated 22   Not indicated: 3%
Expense 14   Expense: 2%
Change in health plan coverage 10   Change in health plan coverage: 1%

See all 743 patients who’ve stopped taking Baclofen

Currently Taking Baclofen

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Baclofen

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations

Adherence

Taking treatment as prescribed

Adherence of Baclofen

Always
609 67%
Usually
181 20%
Sometimes
77 9%
Never
38 4%

Burden

Difficulty being on treatment

Burden of Baclofen

Very
45 5%
Somewhat
67 7%
A little
124 14%
Not at all
669 74%

Cost

Paid out of pocket

Cost of Baclofen

$200+
4 1%
$100-199
5 1%
$50-99
10 2%
$25-49
43 7%
< $25
534 90%

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212 patient evaluations for Baclofen

  • heathercf75
    Sex: F
    Data Quality: 3 stars
    MS: 18 yrs
    Type: Relapsing-Remitting
    Sensation: Moderate
    Overall: Mild
    Cognition: moderate
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: mild
    Walking: moderate
  • 40539-thumb
  • See heathercf75's full Baclofen history
Purpose: MS (Multiple Sclerosis) (Started Jan 19, 2001)
Date Dosage Perceived effectiveness Side Effects Adherence Burden
Jun 11, 2013 60 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
  • CURLYWINGS
    Sex: M
    Data Quality: 3 stars
    MS: 10 yrs
    Type: Primary Progressive
    Sensation: None
    Overall: None
    Cognition: none
    Vision: none
    Speech: none
    Swallowing: none
    Upper limb: moderate
    Walking: moderate
  • Portrait_default_thumb
  • See CURLYWINGS's full Baclofen history
Purposes: MS (Multiple Sclerosis) and Stiffness/Spasticity (Started Nov 19, 2007)
Date Dosage MS (Multiple Sclerosis) Perceived effectiveness Stiffness/Spasticity Perceived effectiveness Side Effects Adherence Burden
Jun 01, 2013 50 mg Daily Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major Led_efficacy_4Led_efficacy_4Led_efficacy_4Led_efficacy_4Major MildMildMildMildMild AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
  • trpaquinn
    Sex: F
    Data Quality: 3 stars
    MS: 16 yrs
    Type: Secondary Progressive
    Sensation: Moderate
    Overall: Moderate
    Cognition: moderate
    Vision: moderate
    Speech: mild
    Swallowing: mild
    Upper limb: moderate
    Walking: severe
  • 8659-thumb
  • See trpaquinn's full Baclofen history
Purposes: Stiffness/Spasticity and MS (Multiple Sclerosis) (Started Oct 28, 2011)
Date Dosage Stiffness/Spasticity Perceived effectiveness MS (Multiple Sclerosis) Perceived effectiveness Side Effects Adherence Burden
May 15, 2013 20 mg Daily Led_efficacy_3Led_efficacy_3Led_efficacy_3Led_defaultModerate ?Can't tell NoneNoneNoneNoneNone AlwaysAlwaysAlwaysAlwaysAlways Not at allNot at allNot at allNot at allNot at all
  • Icon_thumb_off 0 helpful marks
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What is baclofen?

Baclofen is a muscle relaxer and an antispastic agent.

Baclofen is used to treat muscle symptoms caused by multiple sclerosis, including spasm, pain, and stiffness.

Baclofen may also be used for other purposes not listed in this medication guide.


Precautions

Do not use this medication if you are allergic to baclofen.

Before taking baclofen, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;
  • epilepsy or other seizure disorder; or
  • a history of stroke or blood clots.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether baclofen passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more sensitive to the effects of this medicine.

Do not give this medication to a child younger than 12 years old.

Baclofen can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It can increase some of the side effects of baclofen.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by baclofen.

Do not use baclofen at a time when muscle tone is needed to assure safe balance and movement for certain activities. In some situations, it may endanger your physical safety to be in a state of reduced muscle tone.

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Instructions

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include muscle weakness, vomiting, drowsiness, dilated or pinpoint pupils, weak or shallow breathing, fainting, or coma.

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

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Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • seizure (convulsions);
  • confusion, hallucinations; or
  • an uneven heartbeat.

Less serious side effects may include:

  • drowsiness, dizziness, weakness, tired feeling;
  • headache;
  • sleep problems (insomnia);
  • nausea, constipation; or
  • urinating more often than usual.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

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Interactions

There may be other drugs that can affect baclofen. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Other Names

Lioresal, Lioresal Intrathecal, and baclofen

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Disclaimer

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2004 Cerner Multum, Inc. Version 2.05. Revision date 8/23/04

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