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What is Mesalamine?

Mesalamine, a derivative of 5-aminosalicylic acid, is an anti-inflammatory agent. Orally it is used to treat and maintain remission of mild to moderate ulcerative colitis. Rectal administration is used to treat active mild-to-moderate distal ulcerative colitis, proctosigmoiditis, or proctitis.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Ulcerative colitis 46 17 Efficacy_major Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Crohn's Disease 45 8 Efficacy_moderate Efficacy_slight Efficacy_none Efficacy_cant_tell
Ulcerative colitis 12 5 Efficacy_major Efficacy_moderate Efficacy_slight
Other 9 2 Efficacy_none Efficacy_cant_tell
Crohn's disease and Colitis 5 0
Colitis 5 2 Efficacy_major

See all 101 patients currently taking Mesalamine

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Reported Side Effects

Side effects as an overall problem

Severe
 1
Moderate
 4
Mild
 7
None
 24

Commonly reported side effects, conditions, and hospitalizations associated with Mesalamine

Hair loss (alopecia) 4
Cramps in legs 1
Cramps in feet 1
Diarrhea 1
Stomach pain 1
None 1

Reported Dosages

Frequently reported dosages based on patients currently taking Mesalamine. See all 34 dosages ►

  2.4 g daily 4.8 g daily 400 mg daily 800 mg daily 1,000 mg daily 1,200 mg daily 2,000 mg daily 2,400 mg daily 3,000 mg daily 4,000 mg daily
  7 Number of Patients: 7 10 Number of Patients: 10 3 Number of Patients: 3 6 Number of Patients: 6 8 Number of Patients: 8 3 Number of Patients: 3 3 Number of Patients: 3 14 Number of Patients: 14 9 Number of Patients: 9 9 Number of Patients: 9  

Reported Stop Reasons

Why Patients Stopped Taking Mesalamine (multiple reasons could be selected)
Reason # Patients Percentage of patients
Did not seem to work 18   Did not seem to work: 47%
Doctor's advice 12   Doctor's advice: 32%
Side effects too severe 8   Side effects too severe: 21%
Other 5   Other: 13%
Course of treatment ended 4   Course of treatment ended: 11%
Personal research 3   Personal research: 8%
Change in health plan coverage 2   Change in health plan coverage: 5%
Not indicated 2   Not indicated: 5%
Expense 1   Expense: 3%

See all 37 patients who’ve stopped taking Mesalamine

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Mesalamine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Stopped Taking Mesalamine

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Mesalamine

Always
 23 64%
Usually
 10 28%
Sometimes
 3 8%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Mesalamine

Very
 3 8%
Somewhat
 10 28%
A little
 9 25%
Not at all
 14 39%

Cost

Paid out of pocket

Cost of Mesalamine

$200+
 1 5%
$100-199
 2 10%
$50-99
 1 5%
$25-49
 3 15%
< $25
 13 65%

See more information, including instructions, precautions, side effects, and interactions.

Report created on February 11, 2012.