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What is Lotronex?

Lotronex® is a brand name for alosetron, a selective 5-HT3 blocker. It is used for the treatment of women with severe diarrhea-predominant irritable bowel syndrome (IBS) who have failed to respond to conventional therapy. Safety and efficacy has not been established in males.

Reported Purpose & Efficacy

Reasons and Efficacy
Purpose # of patients
# of patients with evaluations Efficacy
Major
Moderate
Slight
None
Can’t tell
Bowel irritability 2 1 Efficacy_major
IBS (Irritable Bowel Syndrome) 2 1 Efficacy_major
Diarrhea 1 1 Efficacy_major

See all 3 patients currently taking Lotronex

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Reported Side Effects

Side effects as an overall problem

Severe
 0
Moderate
 0
Mild
 2
None
 0

Commonly reported side effects, conditions, and hospitalizations associated with Lotronex

Constipation 2
Hemorrhoids 1
Slowed digestion 1
Hospitalization 1

Reported Dosages

  0.5 mg daily 2 mg daily
  1 Number of Patients: 1 2 Number of Patients: 2  

Reported Stop Reasons

Why Patients Stopped Taking Lotronex (multiple reasons could be selected)
Reason # Patients Percentage of patients
Expense 1   Expense: 100%

See all 1 patient who’ve stopped taking Lotronex

Reported Duration See details about how long patients take this treatment ▼

Currently Taking Lotronex

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0

Stopped Taking Lotronex

A bar graph

0-1 month 1-3 months 3-6 months 6 months-1year 1-2 years 2 years or more
0
0
0
0
0

Reported Adherence, Burden & Cost See details from patient evaluations ▼

Adherence

Taking treatment as prescribed

Adherence of Lotronex

Always
 1 50%
Usually
 1 50%
Sometimes
 0 0%
Never
 0 0%

Burden

Difficulty being on treatment

Burden of Lotronex

Very
 0 0%
Somewhat
 0 0%
A little
 1 50%
Not at all
 1 50%

Cost

Paid out of pocket

Cost of Lotronex

$200+
 1 100%
$100-199
 0 0%
$50-99
 0 0%
$25-49
 0 0%
< $25
 0 0%

See more information, including instructions, precautions, side effects, and interactions.

Report created on May 24, 2012.